Rendo-Urteaga Tara, de Moraes Augusto César Ferreira, Collese Tatiana Sadalla, Manios Yannis, Hagströmer María, Sjöström Michael, Kafatos Anthony, Widhalm Kurt, Vanhelst Jérémy, Marcos Ascensión, González-Gross Marcela, De Henauw Stefaan, Ciarapica Donatella, Ruiz Jonatan R, España-Romero Vanesa, Molnár Dénes, Carvalho Heráclito B, Moreno Luis A
Youth/Child and cARdiovascular Risk and Environmental (YCARE) Research Group, School of Medicine, University of São Paulo, São Paulo, Brazil; Growth, Exercise, NUtrition and Development (GENUD) Research Group, School of Health Science (EUCS), University of Zaragoza, Zaragoza, Spain.
Youth/Child and cARdiovascular Risk and Environmental (YCARE) Research Group, School of Medicine, University of São Paulo, São Paulo, Brazil; Growth, Exercise, NUtrition and Development (GENUD) Research Group, School of Health Science (EUCS), University of Zaragoza, Zaragoza, Spain.
Int J Cardiol. 2015;186:186-95. doi: 10.1016/j.ijcard.2015.03.176. Epub 2015 Mar 17.
BACKGROUND/OBJECTIVE: Increased physical activity (PA) and decreased sedentary behaviors (SBs) may have beneficial effects on cardio-metabolic risk in adolescents. The aim of this study was to examine the associations between independent/combined effects of PA and SB with individual/clustered cardio-metabolic risk factors.
A sample of 769 adolescents (12.5-17.5 years) from the HELENA cross-sectional study (Healthy Lifestyle in Europe by Nutrition in Adolescence) and with valid data on metabolic risk factors were included.
Concerning moderate-to-vigorous-PA (MVPA) and vigorous-PA (VPA), measured with accelerometers, girls tended to do more MVPA (36%) and VPA (114%) than boys. Unadjusted analyses show a positive association between "PA ≥ 60 min/d; SB ≥ 2 h" and the ratio TC/HDL-c (β = 0.27; 95%CI 0.01 to 0.52; p < 0.05), and a negative association between "MVPA ≥ 60 min/d; SB < 2h" with the ∑ 4Skinfolds (β = -0.32; 95%CI -0.61 to -0.02; p<0.05). Moreover, "SB ≥ 2 h/d" was associated with increased cardio-metabolic risk (PR 1.59; 95%CI 1.05 to 2.39; p < 0.05), while "PA ≥ 60 min/d; SB < 2h" had a protective effect against cardio-metabolic risk (PR 0.48; 95%CI 0.25 to 0.91; p < 0.05). After adjustment for potential confounders, a positive association between SB and ∑ 4Skinfolds was shown (β = 0.28; 95%CI 0.04 to 0.53; p < 0.05). Furthermore, VO2max (mL/kg/min) tends to increase in those participants who do higher VPA and less SB (p = 0.042), and there was a protective effect of "VPA ≥ 30 min/d; SB < 2h" against cardio-metabolic risk (PR 0.24; 95%CI 0.07 to 0.85; p < 0.05).
The current study suggests that adolescents should be encouraged to decrease sedentary lifestyle and increase physical activity, especially vigorous physical activity, in order to reduce cardio-metabolic risk.
背景/目的：增加身体活动（PA）和减少久坐行为（SBs）可能对青少年的心血管代谢风险产生有益影响。本研究的目的是探讨PA和SB的独立/联合作用与个体/聚类心血管代谢风险因素之间的关联。
纳入来自HELENA横断面研究（欧洲青少年营养健康生活方式研究）的769名青少年（12.5 - 17.5岁），他们有关于代谢风险因素的有效数据。
关于用加速度计测量的中度至剧烈身体活动（MVPA）和剧烈身体活动（VPA），女孩的MVPA（36%）和VPA（114%）往往比男孩更多。未调整分析显示，“PA≥60分钟/天；SB≥2小时”与总胆固醇/高密度脂蛋白胆固醇比值之间存在正相关（β = 0.27；95%置信区间0.01至0.52；p < 0.05），“MVPA≥60分钟/天；SB < 2小时”与4皮褶厚度总和之间存在负相关（β = -0.32；95%置信区间-0.61至-0.02；p < 0.05）。此外，“SB≥2小时/天”与心血管代谢风险增加相关（风险比1.59；95%置信区间1.05至2.39；p < 0.05），而“PA≥60分钟/天；SB < 2小时”对心血管代谢风险有保护作用（风险比0.48；95%置信区间0.25至0.91；p < 0.05）。在对潜在混杂因素进行调整后，显示SB与4皮褶厚度总和之间存在正相关（β = 0.28；95%置信区间0.04至0.53；p < 0.05）。此外，进行较高强度VPA且较少SB的参与者的最大摄氧量（毫升/千克/分钟）往往会增加（p = 0.042），并且“VPA≥30分钟/天；SB < 2小时”对心血管代谢风险有保护作用（风险比0.24；95%置信区间0.07至0.85；p < 0.05）。
当前研究表明，应鼓励青少年减少久坐生活方式并增加身体活动，尤其是剧烈身体活动，以降低心血管代谢风险。
