Garout Wallaa A, Kurdi Hassan S, Shilli Abdulrahman H, Kari Jameela A
Department of Pediatrics, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia. E-mail.
Saudi Med J. 2015 Apr;36(4):497-501. doi: 10.15537/smj.2015.4.10770.
To investigate the most common underlying organisms, and associated urological anomalies in children presenting with urinary tract infection (UTI).
Retrospectively, all children with confirmed UTI between October 2013 and February 2014 were evaluated at King Abdulaziz University Hospital, Riyadh, Kingdom of Saudi Arabia. The electronic files of 279 children presenting with UTI, aged less than 5 years were reviewed.
A total of 153 patients (85 males) with a mean (SD) age of 15 (19.86) months were included in the study. Recurrent UTI was present in 45.1%. Urine collection in children less than 2 years of age was through trans-urethral catheterization in 69.4%, while midstream urine was the main method in those above 2 years (78.6%). Escherichia coli (E. coli) was the causative organism in 41.2% of first UTI. The second most common organism was Klebsiella Pneumoniae, seen in 19.6%. Urological anomalies were found in 28.1% of the overall study population. Ninety percent of those with single UTI did not have anomalies. However, urological anomalies were reported in 50.7% of those with recurrent episodes of UTI (p less than 0.005). Non-E. coli cases were associated with a higher percentage of abnormal renal ultrasonography results (p=0.006).
Escherichia coli was the most common causative organism for UTI, and a single episode of UTI signified normal urological anatomy.
调查患有尿路感染（UTI）的儿童中最常见的潜在病原体及相关泌尿系统异常情况。
回顾性分析2013年10月至2014年2月期间在沙特阿拉伯利雅得阿卜杜勒阿齐兹国王大学医院确诊为UTI的所有儿童。对279例年龄小于5岁的UTI患儿的电子病历进行了回顾。
本研究共纳入153例患者（85例男性），平均（标准差）年龄为15（19.86）个月。复发性UTI占45.1%。2岁以下儿童通过经尿道导尿收集尿液的比例为69.4%，而2岁以上儿童以清洁中段尿为主要收集方法（78.6%）。大肠杆菌（E. coli）是41.2%的首次UTI的致病病原体。第二常见的病原体是肺炎克雷伯菌，占19.6%。在整个研究人群中，发现28.1%存在泌尿系统异常。90%的单发UTI患儿没有异常。然而，在复发性UTI患儿中，有50.7%报告存在泌尿系统异常（p<0.005）。非大肠杆菌病例的肾脏超声检查异常结果百分比更高（p=0.006）。
大肠杆菌是UTI最常见的致病病原体，单发UTI提示泌尿系统解剖结构正常。
