Ouellet-Plamondon Clairélaine, Rousseau Cecile, Nicole Luc, Abdel-Baki Amal
Except for Dr. Rousseau, the authors are with the Department of Psychiatry, Université de Montréal, Quebec, Canada. Dr. Rousseau is with the Department of Psychiatry, McGill University, Quebec. Send correspondence to Dr. Abdel-Baki (e-mail:
Psychiatr Serv. 2015 Jul;66(7):757-9. doi: 10.1176/appi.ps.201300284. Epub 2015 Mar 31.
The study compared engagement in treatment and medication adherence of immigrants and nonimmigrants in early intervention services for persons with first-episode psychosis.
This two-year longitudinal prospective cohort study recruited patients with first-episode psychosis who were entering early intervention services in Montreal, Canada (N=223). Data on sociodemographic characteristics, symptoms, and social functioning were collected annually.
At two years, immigrants had more than three times the odds of attrition than nonimmigrants after the analysis controlled for potential confounding factors (first-generation immigrants: odds ratio [OR]=3.11, 95% confidence interval [CI]=1.01-9.57, p=.049); second-generation immigrants: OR=3.65, CI=1.07-12.50, p=.039). Medication adherence was similar among those who remained in the programs.
During the two years after entering a program for first-episode psychosis, immigrants were more likely than nonimmigrants to disengage from treatment. Further research is warranted to understand this phenomenon and to improve the ability of services to engage immigrants with first-episode psychosis.
本研究比较了首次发作精神病患者早期干预服务中移民和非移民的治疗参与度及药物依从性。
这项为期两年的纵向前瞻性队列研究招募了在加拿大蒙特利尔进入早期干预服务的首次发作精神病患者（N = 223）。每年收集社会人口学特征、症状及社会功能数据。
在对潜在混杂因素进行分析控制后，两年时移民退出治疗的几率是非移民的三倍多（第一代移民：比值比[OR]=3.11，95%置信区间[CI]=1.01 - 9.57，p = 0.049）；第二代移民：OR = 3.65，CI = 1.07 - 12.50，p = 0.039）。留在项目中的患者药物依从性相似。
在进入首次发作精神病项目后的两年里，移民比非移民更有可能退出治疗。有必要进一步研究以了解这一现象，并提高服务机构让首次发作精神病移民参与治疗的能力。
