Ghadiri Vasfi Mohammad, Moradi-Lakeh Maziar, Esmaeili Nazanin, Soleimani Naser, Hajebi Ahmad
All of the authors are with the Iran University of Medical Sciences, Tehran, Islamic Republic of Iran, where Dr. Ghadiri Vasfi and Dr. Hajebi are with the Mental Health Research Center and the Faculty of Behavioral Sciences and Mental Health, Dr. Moradi-Lakeh is with the Department of Community Medicine, and Ms. Esmaeili and Mr. Soleimani are with the Department of Psychology in Mental Hospital. Dr. Moradi-Lakeh is also with the Institute for Health Metrics and Evaluation, Seattle, Washington. Send correspondence to Dr. Hajebi (e-mail:
Psychiatr Serv. 2015 Apr 1;66(4):373-80. doi: 10.1176/appi.ps.201400111. Epub 2014 Dec 15.
This study aimed to determine whether aftercare services reduced the number of rehospitalizations and length of hospital stay among patients with severe mental disorders.
A total of 120 patients with schizophrenia and schizoaffective or bipolar disorder between the ages of 15 and 65 were recruited from 2010 to 2012 for a randomized controlled trial. The participants were followed up for 20 months after discharge from a university-affiliated hospital in Tehran, Iran. The selection procedure was random sampling. Sixty patients received aftercare services, which included treatment follow-up, family psychoeducation, and patient social skills training, and 60 patients received treatment as usual. Number of hospitalizations and length of hospital stay were primary outcome measures, and severity of psychopathology and severity of illness were secondary outcome measures. The quantitative primary and secondary outcomes measures were compared by using repeated-measures analysis.
Three members of the control group did not complete the study. The cumulative number of hospitalizations during the follow-up period was 55 for the control group and 26 for the intervention group. Length of stay was significantly greater in the control group compared with the intervention group (rate ratio=2.38, 95% confidence interval=2.17-2.62). Psychopathology was less severe in the intervention group compared with the control group (p<.001).
Aftercare services are efficacious for reducing both the need for rehospitalization and the severity of psychopathology.
本研究旨在确定后续照护服务是否能减少重症精神障碍患者的再住院次数及住院时间。
2010年至2012年,从15至65岁的精神分裂症、分裂情感性障碍或双相情感障碍患者中招募了120名患者,进行一项随机对照试验。参与者在伊朗德黑兰一家大学附属医院出院后接受了20个月的随访。选择程序为随机抽样。60名患者接受了后续照护服务,包括治疗随访、家庭心理教育和患者社交技能培训,60名患者接受常规治疗。住院次数和住院时间为主要结局指标,精神病理学严重程度和疾病严重程度为次要结局指标。通过重复测量分析比较定量的主要和次要结局指标。
对照组有3名成员未完成研究。随访期间,对照组的累计住院次数为55次,干预组为26次。与干预组相比,对照组的住院时间明显更长(率比=2.38,95%置信区间=2.17 - 2.62)。与对照组相比,干预组的精神病理学症状较轻(p<0.001)。
后续照护服务在减少再住院需求和精神病理学严重程度方面均有效。