Lorberbaum David S, Barolo Scott
Department of Cell and Developmental Biology and Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Department of Cell and Developmental Biology and Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Curr Biol. 2015 Mar 30;25(7):R290-3. doi: 10.1016/j.cub.2015.01.039.
Some transcriptional enhancers work best with one type of promoter, while ignoring others. How widespread is such specificity across the genome? A new study finds that, in a fair fight, most enhancers prefer to activate promoters resembling those of their parent genes.
一些转录增强子与一种启动子配合效果最佳，而对其他启动子则不予理会。这种特异性在全基因组中普遍程度如何？一项新研究发现，在公平竞争的情况下，大多数增强子更倾向于激活与其亲本基因的启动子相似的启动子。
