新西兰学龄前儿童金黄色葡萄球菌和化脓性链球菌定植情况

Colonisation with Staphylococcus aureus and Streptococcus pyogenes in New Zealand preschool children.

作者信息

Berry Sarah, Morton Susan, Atatoa Carr Polly, Marks Emma, Ritchie Stephen, Upton Arlo, Williamson Debbie, Grant Cameron

机构信息

Growing Up in New Zealand, PO Box 18288, Glen Innes, Auckland 1743, New Zealand.

出版信息

N Z Med J. 2015 Mar 13;128(1410):60-7.

PMID:25829040

Abstract

AIM

To describe colonisation patterns of Staphylococcus aureus (S. aureus) and Streptococcus pyogenes (S. pyogenes) among pre-school children in New Zealand.

METHOD

Anterior nasal, oropharyngeal, and antecubital fossa swabs were collected from a diverse sample of 139 New Zealand children aged 4 years. Swabs were cultured for S. aureus and S. pyogenes. S. aureus isolates were tested for antibiotic susceptibility.

RESULTS

S. aureus colonisation was more prevalent than S. pyogenes colonisation; 54% of the children were colonised with S. aureus whereas only 16% were colonised with S. pyogenes, at one or more sampling sites (P<0.0001). S. aureus was present in a larger proportion of swabs obtained from the anterior nasal (39%, P<0.0001) or oropharynx (32%, P=0.0002) than from the antecubital fossa (14%). S. pyogenes was present in a larger proportion of swabs obtained from the oropharynx (16%) than either the anterior nasal (4%, P=0.001) or the antecubital fossa (2%, P<0.0001).

CONCLUSION

S. aureus and S. pyogenes are prevalent at superficial sites in preschool children in NZ, with S. aureus colonisation more prevalent than S. pyogenes colonisation. Colonisation frequency varies by site for both pathogens; S. aureus is more prevalent in the anterior nares and oropharynx while S. pyogenes is more prevalent in the oropharynx.

摘要

目的

描述新西兰学龄前儿童中金黄色葡萄球菌（金葡菌）和化脓性链球菌（化脓链球菌）的定植模式。

方法

从139名4岁的新西兰儿童的不同样本中采集前鼻、口咽和肘前窝拭子。对拭子进行金葡菌和化脓链球菌培养。对金葡菌分离株进行抗生素敏感性测试。

结果

金葡菌定植比化脓链球菌定植更普遍；在一个或多个采样部位，54%的儿童被金葡菌定植，而只有16%被化脓链球菌定植（P<0.0001）。从鼻前（39%，P<0.0001）或口咽（32%，P=0.0002）获得的拭子中，金葡菌的比例高于肘前窝（14%）。从口咽获得的拭子中化脓链球菌的比例（16%）高于鼻前（4%，P=0.001）或肘前窝（2%，P<0.0001）。