Subtil João, Rodrigues João Carlos, Reis Lúcia, Freitas Luís, Filipe Joana, Santos Alberto, Macor Carlos, Duarte Aida, Jordao Luisa
Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
Departamento de Doenças Infeciosas (DDI), Instituto Nacional de Saúde Dr. Ricardo Jorge (INSA), Avenida Padre Cruz, 1649-016, Lisbon, Portugal.
Eur Arch Otorhinolaryngol. 2017 Apr;274(4):1933-1938. doi: 10.1007/s00405-017-4493-z. Epub 2017 Feb 18.
Adenoids play a key role in both respiratory and ear infection in children. It has also been shown that adenoidectomy improves these symptoms in this population. The main goal of the present study was to evaluate adenoid bacterial colonization and document a possible relation with infectious respiratory disease. A prospective observational study was designed to evaluate the proposed hypothesis in a paediatric population submitted to adenoidectomy by either infectious or non-infectious indications and compare these two cohorts. A total of 62 patients with ages ranging from 1 to 12 years old were enrolled in the study. Adenoid surface, adenoid core and middle meatus microbiota were compared. A close association between adenoid colonization and nasal infection was found, supporting that adenoids may function as bacterial reservoir for upper airway infection. The obtained results also contribute to explain the success of adenoidectomy in patients with infectious indications.
腺样体在儿童呼吸道和耳部感染中起着关键作用。研究还表明，腺样体切除术可改善该人群的这些症状。本研究的主要目的是评估腺样体细菌定植情况，并记录其与感染性呼吸道疾病之间的可能关系。一项前瞻性观察性研究旨在评估在因感染性或非感染性指征接受腺样体切除术的儿科人群中所提出的假设，并比较这两个队列。共有62名年龄在1至12岁之间的患者纳入该研究。对腺样体表面、腺样体核心和中鼻道微生物群进行了比较。发现腺样体定植与鼻腔感染之间存在密切关联，支持腺样体可能作为上呼吸道感染的细菌储存库的观点。所获得的结果也有助于解释腺样体切除术在有感染性指征患者中的成功原因。
