氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在甲状腺癌患者管理及预后中的价值
Value of Fluorodeoxyglucose PET/Computed Tomography Patient Management and Outcomes in Thyroid Cancer.
作者信息
Ciarallo Anthony, Marcus Charles, Taghipour Mehdi, Subramaniam Rathan M
机构信息
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA.
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA.
出版信息
PET Clin. 2015 Apr;10(2):265-78. doi: 10.1016/j.cpet.2014.12.009. Epub 2015 Jan 29.
"Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes."
氟脱氧葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）最常用于监测碘难治性分化型甲状腺癌，这类癌症在治疗后甲状腺球蛋白水平升高。本文评估了FDG-PET/CT对临床管理的影响以及阳性扫描结果的预后意义。在所回顾的研究中，FDG-PET/CT改变了14%至78%疑似复发患者的治疗过程，阳性扫描结果与较差的生存率相关。文献中对间变性和髓样甲状腺癌也有类似结论，尽管由于这些亚型的患病率较低，相关研究较少。
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