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一例近乎致命的哮喘病例:体外膜肺氧合作为挽救治疗的作用。

A case of near fatal asthma: The role of ECMO as rescue therapy.

作者信息

Alzeer Abdulaziz H, Al Otair Hadil A, Khurshid Syed Moazzum, Badrawy Sherif El, Bakir Bakir M

机构信息

Department of Critical Care, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

King Fahad Cardiac Centre, King Khalid University Hospital, Riyadh, Saudi Arabia.

出版信息

Ann Thorac Med. 2015 Apr-Jun;10(2):143-5. doi: 10.4103/1817-1737.152461.

DOI:10.4103/1817-1737.152461
PMID:25829967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4375744/
Abstract

We report a case of an adolescent with near fatal asthma (NFA). He presented with severe hypoxemia and lifethreatening acidemia, who failed to respond to conventional therapy. His hospital course was complicated by barotrauma and hemodynamic instability. Early introduction of extracorporeal membrane oxygenation (ECMO) led to dramatic improvement in gas exchange and lung mechanics. This case illustrates the important role of ECMO as salvage therapy in NFA.

摘要

我们报告一例青少年近致死性哮喘(NFA)病例。他表现为严重低氧血症和危及生命的酸血症,对传统治疗无反应。他的住院过程因气压伤和血流动力学不稳定而复杂化。早期引入体外膜肺氧合(ECMO)使气体交换和肺力学得到显著改善。该病例说明了ECMO作为NFA挽救治疗的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e59/4375744/f127df4c9ccb/ATM-10-143-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e59/4375744/f127df4c9ccb/ATM-10-143-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e59/4375744/f127df4c9ccb/ATM-10-143-g001.jpg

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Curr Opin Crit Care. 2013 Feb;19(1):38-43. doi: 10.1097/MCC.0b013e32835c2ac8.
2
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JAMA. 2009 Nov 4;302(17):1888-95. doi: 10.1001/jama.2009.1535. Epub 2009 Oct 12.
3
Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center database.
青少年及成年患者的急性重度哮喘:评估与管理的当前观点
J Clin Med. 2019 Aug 22;8(9):1283. doi: 10.3390/jcm8091283.
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The Saudi Initiative for Asthma - 2019 Update: Guidelines for the diagnosis and management of asthma in adults and children.《沙特哮喘倡议 - 2019年更新版:成人及儿童哮喘诊断与管理指南》
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The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children.《沙特哮喘倡议 - 2016年更新版:成人及儿童哮喘诊断与管理指南》
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