3特斯拉磁共振成像中乳腺病变的扩散加权成像及表观扩散系数
Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions.
作者信息
Caivano Rocchina, Villonio Antonio, D' Antuono Felice, Gioioso Matilde, Rabasco Paola, Iannelli Giancarlo, Zandolino Alexis, Lotumolo Antonella, Dinardo Giuseppina, Macarini Luca, Guglielmi Giuseppe, Cammarota Aldo
机构信息
1IRCCS-CROB, Rionero in Vulture , Italy.
出版信息
Cancer Invest. 2015 May;33(5):159-64. doi: 10.3109/07357907.2015.1019674. Epub 2015 Apr 1.
OBJECTIVE
To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions.
METHODS
110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results.
RESULTS
MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm(2)/s, respectively (p < .05).
CONCLUSIONS
DWI and ADC-values could help distinguishing malignant and benign breast masses.
目的
在一项关于乳腺癌的3T磁共振成像（MRI）研究中评估扩散加权成像（DWI）和表观扩散系数（ADC）的效用。具体而言，该研究旨在根据组织学对良性或恶性病变的ADC值进行分类。
方法
回顾性分析110例采用MRI-DWI序列并对ADC进行定量评估的乳腺MRI检查。分析MRI-DWI及活检结果，并将ADC值与组织学结果进行比较。
结果
MRI显示敏感性为95.5%，特异性为83.7%。良性和恶性病变的平均ADC值分别为2.06±0.19和1.03±0.07mm²/s（p<.05）。
结论
DWI和ADC值有助于鉴别乳腺良恶性肿块。
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