McKenna G, Hayes M, Burke F M
Eur J Prosthodont Restor Dent. 2014 Sep;22(3):98-100.
Acromegaly is a condition which results from an excess of growth hormone produced by the pituitary gland after epiphyseal plate closure at puberty. The most common cause of acromegaly is a benign pituitary adenoma. Acromegaly is characterised by enlargement of the hands, feet, nose and ears; expansion of the skull and pronounced brow protrusion. From an oral standpoint, the most relevant symptoms are mandibular protrusion, spacing of the lower teeth and macroglossia. A 46 year-old patient was referred to University Dental School and Hospital by her General Dental Practitioner. The patient had been diagnosed with acromegaly and was receiving medical care from a consultant endocrinologist. The patient was partially dentate with only her lower anterior dentition remaining. She was wearing a complete upper denture but was unable to function effectively due to a lack of occlusal support. Treatment comprised non-surgical periodontal management, construction of upper and lower removable prostheses in a class III relationship and composite restorations on the remaining lower teeth.
肢端肥大症是一种在青春期骨骺板闭合后，由垂体分泌过多生长激素所致的病症。肢端肥大症最常见的病因是垂体良性腺瘤。肢端肥大症的特征表现为手部、足部、鼻子和耳朵增大；颅骨扩张以及明显的眉弓突出。从口腔方面来看，最相关的症状是下颌前突、下牙间隙增宽和巨舌症。一名46岁的患者由其普通牙科医生转诊至大学牙科学院及医院。该患者已被诊断为肢端肥大症，正在接受内分泌科顾问医生的治疗。患者为部分牙列缺失，仅保留了下前牙列。她佩戴着一副全口上颌义齿，但由于缺乏咬合支持而无法有效发挥功能。治疗包括非手术牙周管理、制作III类关系的上下可摘局部义齿以及对剩余下牙进行复合树脂修复。
