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用于犬猫的一种带索引的放射治疗头部定位装置的验证

VALIDATION OF AN INDEXED RADIOTHERAPY HEAD POSITIONING DEVICE FOR USE IN DOGS AND CATS.

作者信息

Hansen Katherine S, Théon Alain P, Dieterich Sonja, Kent Michael S

机构信息

Department of Surgical and Radiological Sciences, VM: Surgery Radiology, University of California, Davis, CA, USA, 95616.

UC Davis Comprehensive Cancer Center, Radiation Oncology, Sacramento, CA, USA.

出版信息

Vet Radiol Ultrasound. 2015 Jul-Aug;56(4):448-55. doi: 10.1111/vru.12257. Epub 2015 Apr 2.

Abstract

Setup variability affects the appropriate delivery of radiation and informs the setup margin required to treat radiation patients. Twenty-four veterinary patients with head and neck cancers were enrolled in this prospective, cross-sectional study to determine the accuracy of an indexed board immobilization device for positioning. Couch position values were defined at the first treatment based on setup films. At subsequent treatments, patients were moved to the previously defined couch location, orthogonal films were acquired, table position was modified, and displacement was recorded. The mean systematic displacement, random displacement, overall displacement, and mean displacement values of the three-dimensional (3D) vector were calculated. Three hundred thirty-two pairs of orthogonal setup films were analyzed for displacement in cranial-caudal, lateral, and dorsal-ventral directions. The mean systematic displacements were 0.5, 0.8, and 0.5 mm, respectively. The mean random displacements were 1.0, 1.1, and 0.7 mm, respectively. The overall displacements were 1.1, 1.4, and 0.9 mm, respectively. The mean 3D vector value was 1.6 mm with a standard deviation of 1.2 mm. Ninety-five percent of the vectors were <3.6 mm. These values were compared to data obtained with a previously used immobilization device. A t-test was used to compare the two devices. The 3D vector, random displacement in all directions, and overall displacement in the cranial-caudal and dorsal-ventral directions were significantly smaller than displacements with the previous device. The precision and accuracy of the indexed board device was superior to the historical head and neck device.

摘要

摆位变异性会影响放疗的精确实施,并为放疗患者确定所需的摆位边界提供依据。本前瞻性横断面研究纳入了24例患有头颈癌的兽医患者,以确定一种索引板固定装置用于定位的准确性。在首次治疗时根据摆位片确定治疗床位置值。在后续治疗中,将患者移至先前确定的治疗床位置,获取正交片,调整治疗床位置并记录位移。计算三维(3D)向量的平均系统位移、随机位移、总位移和平均位移值。分析了332对正交摆位片在头-尾、侧方和背-腹方向的位移。平均系统位移分别为0.5、0.8和0.5mm。平均随机位移分别为1.0、1.1和0.7mm。总位移分别为1.1、1.4和0.9mm。平均3D向量值为1.6mm,标准差为1.2mm。95%的向量<3.6mm。将这些值与使用先前固定装置获得的数据进行比较。采用t检验比较这两种装置。索引板装置的3D向量、所有方向的随机位移以及头-尾和背-腹方向的总位移均显著小于先前装置的位移。索引板装置的精度和准确性优于既往的头颈装置。

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