Reddy Deveshni, Morrow Brenda M, Argent Andrew C
Paediatric Intensive Care Unit, Red Cross War Memorial Children's Hospital, Rondebosch, Cape Town, 7700, South Africa Department of Paediatrics and Child Health, University of Cape Town, Cape Town, 7700, South Africa.
Department of Paediatrics and Child Health, University of Cape Town, Cape Town, 7700, South Africa
J Trop Pediatr. 2015 Jun;61(3):182-7. doi: 10.1093/tropej/fmv017. Epub 2015 Mar 31.
To describe and compare characteristics and outcomes of patients colonized or infected with Acinetobacter baumannii (cases) to a control group.
A retrospective case-controlled study of patients admitted to a South African paediatric intensive care unit (PICU) between January and December 2010.
Acinetobacter baumannii was isolated in 194 patients. Mortality was similar between cases (9.3%) and controls (9.8%). Median duration of PICU stay and mechanical ventilation in cases vs. controls was 10 vs. 2 (p < 0.0001) and 9 vs. 1 days (p < 0.0001), respectively. Admission diagnosis of traumatic brain injury [adjusted odds ratio (OR): 5.6, 95% CI: 1.2-27.0; p = 0.03] and duration of mechanical ventilation (adjusted OR: 1.4, 95% CI: 1.3-1.5; p < 0.0001) were independently associated with A. baumannii aquisition.
Acinetobacter baumannii acquisition was common and associated with increased morbidity, but not increased mortality.
描述并比较鲍曼不动杆菌定植或感染患者（病例组）与对照组的特征及结局。
对2010年1月至12月间入住南非一家儿科重症监护病房（PICU）的患者进行回顾性病例对照研究。
194例患者分离出鲍曼不动杆菌。病例组（9.3%）和对照组（9.8%）的死亡率相似。病例组与对照组在PICU的中位住院时间分别为10天和2天（p<0.0001），机械通气时间分别为9天和1天（p<0.0001）。创伤性脑损伤的入院诊断[调整优势比（OR）：5.6，95%置信区间（CI）：1.2 - 27.0；p = 0.03]和机械通气时间（调整OR：1.4，95%CI：1.3 - 1.5；p<0.0001）与鲍曼不动杆菌感染独立相关。
鲍曼不动杆菌感染常见，且与发病率增加相关，但与死亡率增加无关。
