Smith Heather, Youn Youngwon, Pilitsis Julie G
Department of Neurosurgery, Albany Medical College, Albany, N.Y., USA.
Stereotact Funct Neurosurg. 2015;93(3):190-3. doi: 10.1159/000380825. Epub 2015 Apr 1.
High-frequency spinal cord stimulation (HFSCS) offers an alternative treatment for chronic refractory pain syndromes nonresponsive to traditional spinal cord stimulation (SCS). Following the conflicting findings of preliminary HFSCS clinical studies performed at 5-10 kHz, this study is the first to report successful clinical usage of 1-kHz frequency SCS with a standard generator.
We used HFSCS in 2 patients who had inadequate relief with traditional SCS. Patient 1 was initially programmed at 40 Hz and a pulse width of 330 μs with bipolar stimulation. After multiple setting adjustments with inadequate pain relief, the patient was reprogrammed to HFSCS at settings of 1.15 kHz, 120 μs, and 5 V. Patient 2 was initially programmed at a frequency of 1.2 kHz and a pulse width of 120 μs, which she favored over the standard setting of 40 Hz and 390 μs pulse width. HFSCS provided optimal pain alleviation and increased quality of life for both patients.
HFSCS at the frequency of 1 kHz offers a new tool for treatment of chronic pain in patients with traditional stimulation settings. Furthermore, most standard SCS batteries are capable of delivering stimulation in this frequency range.
高频脊髓刺激（HFSCS）为对传统脊髓刺激（SCS）无反应的慢性难治性疼痛综合征提供了一种替代治疗方法。在对5-10kHz进行的初步HFSCS临床研究结果相互矛盾之后，本研究首次报告了使用标准发生器成功进行1kHz频率SCS的临床应用。
我们对2例传统SCS治疗效果不佳的患者使用了HFSCS。患者1最初设置为双极刺激，频率40Hz，脉冲宽度330μs。在多次调整设置但疼痛缓解不足后，患者重新设置为HFSCS，设置为1.15kHz、120μs和5V。患者2最初设置为频率1.2kHz，脉冲宽度120μs，她更喜欢这种设置，而不是标准的40Hz和390μs脉冲宽度设置。HFSCS为两名患者都提供了最佳的疼痛缓解并提高了生活质量。
1kHz频率的HFSCS为传统刺激设置下的慢性疼痛患者提供了一种新的治疗工具。此外，大多数标准SCS电池都能够在该频率范围内提供刺激。
