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前庭疾病诊断与治疗的进展:心理物理学与假体

Advances in the diagnosis and treatment of vestibular disorders: psychophysics and prosthetics.

作者信息

Lewis Richard F

机构信息

Department of Otology and Laryngology and Department of Neurology, Harvard Medical School, Boston, Massachusetts 02114

出版信息

J Neurosci. 2015 Apr 1;35(13):5089-96. doi: 10.1523/JNEUROSCI.3922-14.2015.

DOI:10.1523/JNEUROSCI.3922-14.2015
PMID:25834036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4380990/
Abstract

Although vestibular disorders are common and often disabling, they remain difficult to diagnose and treat. For these reasons, considerable interest has been focused on developing new ways to identify peripheral and central vestibular abnormalities and on new therapeutic options that could benefit the numerous patients who remain symptomatic despite optimal therapy. In this review, I focus on the potential utility of psychophysical vestibular testing and vestibular prosthetics. The former offers a new diagnostic approach that may prove to be superior to the current tests in some circumstances; the latter may be a way to provide the brain with information about head motion that restores some elements of the information normally provided by the vestibular labyrinth.

摘要

尽管前庭疾病很常见且常常导致残疾,但它们仍然难以诊断和治疗。由于这些原因,人们对开发新方法以识别外周和中枢前庭异常以及新的治疗选择产生了浓厚兴趣,这些新方法和治疗选择可能会使众多尽管接受了最佳治疗仍有症状的患者受益。在这篇综述中,我重点关注心理物理学前庭测试和前庭假体的潜在效用。前者提供了一种新的诊断方法,在某些情况下可能被证明优于当前的测试;后者可能是一种向大脑提供有关头部运动信息的方式,从而恢复前庭迷路通常提供的一些信息元素。

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本文引用的文献

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Central Integration of Canal and Otolith Signals is Abnormal in Vestibular Migraine.前庭性偏头痛中存在管-耳石信号的中枢整合异常。
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Directional plasticity rapidly improves 3D vestibulo-ocular reflex alignment in monkeys using a multichannel vestibular prosthesis.多通道前庭假体可快速改善猴子的 3D 前庭眼反射定向。
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