Pinder Binny, Lloyd Andrew J, Nafees Beenish, Elkin Eric P, Marley Jerome
ICON plc, Oxford, UK.
ICON plc, San Francisco, CA, USA.
Patient Prefer Adherence. 2015 Mar 9;9:381-8. doi: 10.2147/PPA.S73487. eCollection 2015.
Intermittent catheterization is the gold standard for bladder management in Europe in people with spinal cord injuries. The aim of the present study was to identify and investigate individuals' preferences regarding intermittent self-catheterization (ISC) devices and furthermore investigate the willingness to pay for attributes in ISC devices in the UK, France, and the Netherlands.
A discrete choice experiment survey was conducted to evaluate the patients' perceived value of catheter features. Attributes were selected based upon a literature review of the most important characteristics of catheters and the survey was developed and validated with input from patients and medical experts. Data were analyzed using the conditional logit model whereby the coefficients obtained from the model provided an estimate of the (log) odds ratios of preference for attributes. Willingness to pay was estimated for all levels of the attributes.
Two-hundred and eighty-three participants completed the questionnaire and were included in data analysis. Risk of infection had the highest odds ratios as preferred important attribute for all three countries followed by ease of insertion. "Pre-coated catheters" was found to be valued as the most preferred coating technology across all countries. Out of pocket cost was a significant influence on patients' choice.
Users of ISC perceive the value of convenience (size of catheter), ease of insertion, and reduced risk of infection as the most important features attached to an intermittent catheter. These results are applicable both for the "classic" ISC user as well as for another broad group of catheter dependent individuals.
在欧洲,间歇性导尿是脊髓损伤患者膀胱管理的金标准。本研究的目的是识别并调查个体对间歇性自我导尿(ISC)装置的偏好,此外还调查英国、法国和荷兰患者为ISC装置的属性付费的意愿。
进行了一项离散选择实验调查,以评估患者对导尿管特征的感知价值。根据对导尿管最重要特征的文献综述选择属性,并在患者和医学专家的参与下开发并验证了该调查。使用条件logit模型分析数据,该模型获得的系数提供了对属性偏好的(对数)优势比的估计。对属性的所有水平估计了支付意愿。
283名参与者完成了问卷并纳入数据分析。感染风险在所有三个国家中作为首选的重要属性具有最高的优势比,其次是插入的难易程度。“预涂覆导尿管”被认为是所有国家中最受欢迎的涂层技术。自付费用对患者的选择有重大影响。
ISC使用者认为便利性(导尿管尺寸)、易于插入以及降低感染风险是间歇性导尿管最重要的特征。这些结果适用于“经典”ISC使用者以及另一大类依赖导尿管的个体。