HIV 时代的福尼尔坏疽
Fournier's ganrene in the HIV era.
作者信息
Ngugi Peter, Magoha George, Nyaga Paul
机构信息
University of Nairobi, Department of Surgery.
Marsabit hospital, Department of Surgery.
出版信息
Afr Health Sci. 2014 Dec;14(4):1063-8. doi: 10.4314/ahs.v14i4.38.
BACKGROUND
Fournier's gangrene is a devastating condition that affects mostly patients whose immunity has been reduced. There is increasing evidence for increasing incidence of the disease in those with HIV disease.
OBJECTIVE
To evaluate the presentation, bacteriology and outcome of Fournier's gangrene in our area in recent times in view of the high prevalence in Nairobi and its environs.
RESULTS
One hundred and forty six patients were treated for Fournier's gangrene during the study period; all were male. They had a mean age of 38.6 years (range 2 months - 86 years). HIV infection was the most common associated underlying illness (16.4 %), followed by diabetes mellitus and alcoholism (11%).
CONCLUSIONS
HIV infection is emerging as leading predisposing factor and has overtaken diabetes in predisposing for Fournier's gangrene in Kenyatta National Hospital.
背景
福尼尔坏疽是一种严重疾病，主要影响免疫力低下的患者。越来越多的证据表明，感染艾滋病毒的人群中该疾病的发病率在上升。
目的
鉴于内罗毕及其周边地区该病的高发病率，评估近期我们地区福尼尔坏疽的临床表现、细菌学及治疗结果。
结果
在研究期间，146例患者接受了福尼尔坏疽治疗；均为男性。他们的平均年龄为38.6岁（范围2个月至86岁）。艾滋病毒感染是最常见的相关基础疾病（16.4%），其次是糖尿病和酗酒（11%）。
结论
在肯雅塔国家医院，艾滋病毒感染正成为福尼尔坏疽的主要诱发因素，在诱发该疾病方面已超过糖尿病。
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