Korkmaz Safak, Konuk Onur
a Department of Ophthalmology , Düzce State Hospital , Düzce , Turkey and.
b Department of Ophthalmology , Gazi University Medical School , Ankara , Turkey.
Curr Eye Res. 2016;41(2):159-64. doi: 10.3109/02713683.2015.1008641. Epub 2015 Apr 2.
To compare the long-term visual outcomes after 2-wall (medial-lateral) versus 3-wall (medial-lateral-inferior) orbital decompression combined with fat removal in patients with dysthyroid optic neuropathy (DON).
Records of 68 eyes of 42 patients were retrospectively reviewed. Two-and 3-wall decompression was performed in 41 and 27 eyes, respectively. Transcaruncular approach was used for medial wall decompression. Lateral canthotomy combined with upper eyelid crease incision was used for lateral wall removal, and combined with transconjunctival lower eyelid incision if floor decompression performed. Outcome measures were visual acuity (VA), color vision, Hertel measures, visual field mean deviation (MD) and pattern standard deviation (PSD) Result: The mean follow-up time was 39.3 months (range, 12-72 months). All indicators of visual function significantly improved after 2-and 3-wall decompression. The improvement in VA and color vision was similar between groups. (logMAR VA: 2-wall: 0.52 ± 0.68 versus 3-wall: 0.71 ± 0.86, p = 0.335); (color vision on Ishihara plates: 2-wall: 10.1 ± 8.1 versus 3-wall: 11.6 ± 7.8, p = 0.447). The improvement in MD and PSD were higher after 3-wall decompression (MD: 2-wall: 10.0 ± 5.5 versus 3-wall: 14.3 ± 7.5 dB, p = 0.020); (PSD: 2-wall: 3.5 ± 1.9 versus 3-wall: 4.8 ± 3.0 dB, p = 0.045). Proptosis reduction was higher after 3-wall decompression (2-wall: 5.1 ± 1.3 versus 3-wall: 7.2 ± 1.9 mm, p = 0.0001). New onset diplopia was seen 20% and 28.5% of cases in 2-and 3-wall decompression, respectively. No adnexal/orbital complications were seen in 2-wall group, however orbital hematoma (1 case) and persisting eyelid edema (1 case) were encountered in 3-wall group.
Both 2-and 3-wall orbital decompressions are safe and effective for management of visual dysfunction in DON. Although 3-wall decompression provide better improvement in the parameters of visual field analysis and Hertel measures, new onset diplopia, adnexal/orbital complications are more common with this technique.
比较甲状腺功能障碍性视神经病变(DON)患者行两壁(内侧-外侧)与三壁(内侧-外侧-下壁)眼眶减压联合脂肪去除术后的长期视力预后。
回顾性分析42例患者68只眼的记录。分别对41只眼和27只眼进行了两壁和三壁减压。经泪阜入路行内侧壁减压。外侧眦切开联合上睑皱襞切口用于外侧壁去除,若行下壁减压则联合经结膜下睑切口。观察指标为视力(VA)、色觉、Hertel测量值、视野平均偏差(MD)和模式标准偏差(PSD)。结果:平均随访时间为39.3个月(范围12 - 72个月)。两壁和三壁减压后所有视觉功能指标均显著改善。两组间VA和色觉的改善相似。(logMAR视力:两壁组:0.52±0.68,三壁组:0.71±0.86,p = 0.335);(石原氏色盲检查表色觉:两壁组:10.1±8.1,三壁组:11.6±7.8,p = 0.447)。三壁减压后MD和PSD的改善更高(MD:两壁组:10.0±5.5,三壁组:14.3±7.5 dB,p = 0.020);(PSD:两壁组:3.5±1.9,三壁组:4.8±3.0 dB,p = 0.045)。三壁减压后眼球突出度降低更明显(两壁组:5.1±1.3,三壁组:7.2±1.9 mm,p = 0.0001)。两壁和三壁减压病例中分别有20%和28.5%出现新发复视。两壁组未出现附件/眼眶并发症,然而三壁组出现1例眼眶血肿和1例持续性眼睑水肿。
两壁和三壁眼眶减压治疗DON的视觉功能障碍均安全有效。虽然三壁减压在视野分析参数和Hertel测量值方面改善更好,但该技术新发复视、附件/眼眶并发症更常见。