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甲状腺相关眼病视神经病变致视力下降行紧急内镜眶减压术。

Urgent endoscopic orbital decompression for vision deterioration in dysthyroid optic neuropathy.

机构信息

Department of otolaryngology, Western University, Ontario, London, Canada.

Department of otolaryngology, Western University, Ontario, London, Canada.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun;136(3S):S49-S52. doi: 10.1016/j.anorl.2018.08.007. Epub 2018 Aug 28.

Abstract

AIMS

To report visual acuity outcomes and potential complications in patients undergoing endoscopic transnasal orbital decompression in the setting of acutely deteriorating sight secondary to dysthyroid optic neuropathy (DON) unresponsive to corticosteroid therapy. No previous reports describe vision outcomes in this specific patient population undergoing urgent endoscopic decompression.

MATERIAL AND METHODS

Retrospective case review at a tertiary-care academic hospital. Four patients with DON were identified that underwent urgent endoscopic orbital decompression for acutely deteriorating vision. Three patients underwent a later decompression of the other orbit, yielding seven decompressions in total for acutely deteriorating vision. Operative technique entailed inferior and medial wall decompressions. The posterior limit of medial wall decompression was within the sphenoid, just anterior to the annulus of Zinn to fully decompress the optic nerve. Primary outcome was visual acuity.

RESULTS

In all seven decompressions, visual acuity improved substantially. In 5/7 eyes, preoperative vision was severely impaired at 20/150 or worse. Two eyes had mild and moderate impairment at 20/50 and 20/100. Post-operatively, the moderately and severely impaired eyes improved to 20/60 or better. No complications were encountered.

CONCLUSION

Transnasal endoscopic orbital decompression is a safe, effective treatment for acutely worsening visual loss from DON. All cases demonstrated significant objective improvement in visual acuity. Given the need for later contralateral decompression in 3 patients, consideration should be given to performing bilateral orbital decompressions at the time of surgery.

摘要

目的

报告在甲状腺相关眼病(DON)导致的视力急剧下降而对皮质类固醇治疗无反应的情况下,行内镜经鼻眶减压术的患者的视力结果和潜在并发症。以前没有报告描述过在这种特定的患者群体中进行紧急内镜减压的视力结果。

材料和方法

在一家三级保健学术医院进行回顾性病例研究。确定了 4 例因视力急剧下降而接受紧急内镜眶减压术的 DON 患者。其中 3 例随后对另一只眼进行了减压,总共对 7 只眼进行了减压以改善视力急剧下降的情况。手术技术包括下壁和内侧壁减压。内侧壁减压的后缘位于蝶骨内,就在 Zinn 环的前缘,以充分减压视神经。主要结果是视力。

结果

在所有 7 次减压中,视力都有了显著提高。在 5/7 只眼中,术前视力严重受损,视力为 20/150 或更差。2 只眼的视力轻度和中度受损,为 20/50 和 20/100。术后,中度和重度受损的眼睛提高到 20/60 或更好。未发生并发症。

结论

经鼻内镜眶减压术是治疗 DON 导致的视力急剧下降的一种安全、有效的治疗方法。所有病例的视力均有显著的客观改善。鉴于 3 例患者需要进行对侧减压,应考虑在手术时同时进行双侧眶减压。

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