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Neurosci Biobehav Rev. 2013 Jan;37(1):11-23. doi: 10.1016/j.neubiorev.2012.11.003. Epub 2012 Nov 16.
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J Atten Disord. 2014 Nov;18(8):659-70. doi: 10.1177/1087054712446172. Epub 2012 Jun 1.
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Metacognition in human decision-making: confidence and error monitoring.人类决策中的元认知：信心与错误监测。
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注意缺陷多动障碍成年人错误加工的异常脑激活

Aberrant brain activation of error processing among adults with attention deficit and hyperactivity disorder.

作者信息

Chen Chiao-Yun, Yen Ju-Yu, Yen Cheng-Fang, Chen Cheng-Sheng, Liu Gin-Chung, Liang Chih-Yuan, Ko Chih-Hung

机构信息

Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Psychiatry, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

出版信息

Kaohsiung J Med Sci. 2015 Apr;31(4):179-87. doi: 10.1016/j.kjms.2015.01.001. Epub 2015 Feb 3.

DOI:10.1016/j.kjms.2015.01.001
PMID:25835273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11916387/
Abstract

Individuals with adult attention deficit/hyperactivity disorder (ADHD) have a deficit in their cognitive control. The aim of this study was to reveal the brain correlates of the deficits in response inhibition or error processing in adult ADHD. A total of 29 adults with ADHD and 25 control individuals were recruited. They completed an event-related-design Go/No-go task under functional magnetic resonance imaging scanning. Both the ADHD group and the control group exhibited activation of the frontostriatal network when processing response inhibition. They also exhibited activation of the frontoinsula cortex and anterior cingulate in error processing. Adults with ADHD have a lower brain activation of error processing over the right inferior frontal lobe adjacent to the insula than control individuals. The altered frontoinsula cortex activation may represent the mechanism of error processing deficit among adults with ADHD.

摘要

患有成人注意力缺陷多动障碍（ADHD）的个体存在认知控制缺陷。本研究的目的是揭示成人ADHD在反应抑制或错误处理方面缺陷的脑关联。共招募了29名患有ADHD的成年人和25名对照个体。他们在功能磁共振成像扫描下完成了一项事件相关设计的Go/No-go任务。ADHD组和对照组在处理反应抑制时均表现出额纹状体网络的激活。他们在错误处理时也表现出额岛叶皮质和前扣带回的激活。与对照组相比，患有ADHD的成年人在与岛叶相邻的右下额叶区域的错误处理脑激活较低。额岛叶皮质激活的改变可能代表了成人ADHD患者错误处理缺陷的机制。