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对乙酰氨基酚过量服用后发生致命性静脉曲张出血。

Fatal variceal haemorrhage after paracetamol overdose.

作者信息

Thornton J R, Losowsky M S

机构信息

Department of Medicine, St James's University Hospital, Leeds.

出版信息

Gut. 1989 Oct;30(10):1424-5. doi: 10.1136/gut.30.10.1424.

Abstract

A patient is described where oesophageal varices developed and bled 13 days after a paracetamol overdose. The bleeding was unresponsive to medical management and proved fatal. There was no evidence that the patient had pre-existing liver disease. At necropsy the liver showed severe acute parenchymal necrosis but chronic lesions were absent. The portal vein and hepatic veins were patent.

摘要

本文描述了一名患者,其在对乙酰氨基酚过量服用13天后出现食管静脉曲张并出血。出血对药物治疗无反应,最终导致死亡。没有证据表明该患者先前存在肝脏疾病。尸检显示肝脏有严重的急性实质坏死,但无慢性病变。门静脉和肝静脉通畅。

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