Thornton J R, Losowsky M S
Department of Medicine, St James's University Hospital, Leeds.
Gut. 1989 Oct;30(10):1424-5. doi: 10.1136/gut.30.10.1424.
A patient is described where oesophageal varices developed and bled 13 days after a paracetamol overdose. The bleeding was unresponsive to medical management and proved fatal. There was no evidence that the patient had pre-existing liver disease. At necropsy the liver showed severe acute parenchymal necrosis but chronic lesions were absent. The portal vein and hepatic veins were patent.
本文描述了一名患者，其在对乙酰氨基酚过量服用13天后出现食管静脉曲张并出血。出血对药物治疗无反应，最终导致死亡。没有证据表明该患者先前存在肝脏疾病。尸检显示肝脏有严重的急性实质坏死，但无慢性病变。门静脉和肝静脉通畅。
