Birgisson Natalia E, Zhao Qiuhong, Secura Gina M, Madden Tessa, Peipert Jeffrey F
This research was presented in part at the Annual Meeting of the Infectious Diseases Society in Obstetrics and Gynecology, August 7, 2010, Santa Fe, New Mexico.
J Womens Health (Larchmt). 2015 May;24(5):354-9. doi: 10.1089/jwh.2015.5190. Epub 2015 Apr 2.
Unintended pregnancies are a major public health problem in the United States, and intrauterine devices (IUDs) are among the most effective reversible birth control methods available. Historically, there have been concerns about IUD use and infection among young and/or high-risk women that may increase the risk of pelvic inflammatory disease (PID) and subsequent infertility.
The Contraceptive CHOICE Project (CHOICE) was a prospective cohort study of over 9,000 women 14-45 years of age residing in the St. Louis area who were interested in initiating a new form of reversible contraception. At enrollment, participants were counseled regarding long-acting contraceptive methods with the goal of increasing awareness of all reversible methods available. Participants were also tested for Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) during enrollment and were provided with contraception at no cost for 2-3 years.
We estimate the frequency of self-reported PID in new IUD users compared with women using other contraceptive methods. Among both new IUD users who tested positive for GC and/or CT and those who tested negative, the PID rate was 1% or below.
Our results demonstrate that IUD use is safe for all women, including women at high risk for sexually transmitted infections.
意外怀孕是美国一个主要的公共卫生问题,宫内节育器(IUD)是现有的最有效的可逆避孕方法之一。从历史上看,人们一直担心年轻和/或高危女性使用IUD及感染,这可能会增加盆腔炎(PID)及后续不孕的风险。
避孕选择项目(CHOICE)是一项针对居住在圣路易斯地区9000多名14至45岁、有意开始采用新的可逆避孕方式的女性的前瞻性队列研究。在入组时,向参与者提供长效避孕方法咨询,目的是提高她们对所有可用可逆方法的认识。参与者在入组时还接受了淋病奈瑟菌(GC)和沙眼衣原体(CT)检测,并免费获得2至3年的避孕措施。
我们估计了新使用IUD的女性与使用其他避孕方法的女性相比,自我报告的PID发生率。在GC和/或CT检测呈阳性的新IUD使用者以及检测呈阴性的使用者中,PID发生率均为1%或更低。
我们的结果表明,IUD对所有女性都是安全的,包括性传播感染高危女性。