免疫球蛋白水平分布中的混合现象。
Commingling in the distributions of immunoglobulin levels.
作者信息
McGue M, Gerrard J W, Lebowitz M D, Rao D C
机构信息
Department of Psychology, University of Minnesota, Minn.
出版信息
Hum Hered. 1989;39(4):196-201. doi: 10.1159/000153860.
Commingling in the distributions of five immunoglobulins from a Canadian sample of 810 Caucasians and IgE from a US sample of 935 Caucasians was investigated. For both the Canadian and US samples significant commingling was found in the child's but not the adult's IgE distribution. Contrary to expectations based upon the major gene hypothesis for IgM, we found no evidence for commingling in the IgM distribution. Finally, the distributions of IgA, IgD and IgG all evidenced significant commingling that may be the result of a single gene effect or the operation of a discrete environmental effect.
对来自810名加拿大白种人的样本中的五种免疫球蛋白分布以及来自935名美国白种人的样本中的IgE分布进行了混合情况调查。在加拿大和美国的样本中，均发现儿童的IgE分布存在显著混合，但成人的IgE分布不存在显著混合。与基于IgM的主要基因假说的预期相反，我们没有发现IgM分布存在混合的证据。最后，IgA、IgD和IgG的分布均显示出显著混合，这可能是单个基因效应或离散环境效应作用的结果。
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