Qi Jinlei, Zhang Dapeng, Fu Xiaojing, Li Chengmei, Meng Sining, Dai Min, Liu Hui, Sun Jiangping
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Bill & Melinda Gates foundation China Office, Beijing, China.
PLoS One. 2015 Apr 2;10(4):e0121267. doi: 10.1371/journal.pone.0121267. eCollection 2015.
While the HIV epidemic varies greatly by region and population group throughout China, the HIV incidence among men who have sex with men (MSM) continues to rise at an alarmingly fast pace. We seek to analyze the risk factors associated with HIV infection among MSM recruited from different channels in large urban centers across China, in an attempt to shed light on the design of future targeted intervention strategies.
A total of 33,684 MSM from 14 cities and one province were recruited from July to December 2011. Demographic (e.g. age, marital status, education) and behavioral (e.g. condom use, HIV testing history) data were collected using information collection cards. Blood samples were also collected to test for HIV and Syphilis.
Participants were recruited from five different channels, and all demonstrated distinct characteristics. The overall rate of positive HIV screening was 6.27% and the rate of syphilis infection was 6.50%. Participants recruited from bathhouses had the highest HIV (11.80%) and syphilis infection rates (11.20%). Participants who were infected with syphilis had the highest HIV-positive screening rate (13.75%; 95% CI OR, 2.33-3.06). living in the southwest region of the country (11.64%; OR=2.76, 95%CI OR 2.19-3.47), Being >20 years of age (P<0.001), living in the southwest region of the country (OR=2.76, 95%CI 2.19-3.47), not having sex with female over the previous 3 months (OR=1.27, 95%CI 1.09-1.48), no condom use during the last anal intercourse (OR=1.54, 95%CI 1.39-1.70) and other factors were all associated with a higher probability of having an HIV-positive test result.
Depending on the way they are recruited, more targeted interventions are required to prevent the spread of HIV/AIDS among MSM with different characteristics and behaviors. Results from this study could provide evidence for researchers to conduct further studies and policy-makers to establish more effective and strategic interventions for MSM in China.
虽然中国各地的艾滋病疫情因地区和人群差异很大，但男男性行为者（MSM）中的艾滋病发病率仍在以惊人的速度持续上升。我们试图分析从中国各大城市不同渠道招募的男男性行为者中与艾滋病病毒感染相关的风险因素，以期为未来有针对性的干预策略设计提供线索。
2011年7月至12月，从14个城市和1个省份共招募了33684名男男性行为者。使用信息采集卡收集人口统计学（如年龄、婚姻状况、教育程度）和行为学（如是否使用避孕套、艾滋病检测史）数据。还采集血样检测艾滋病病毒和梅毒。
参与者从五个不同渠道招募，各渠道均呈现出不同特征。艾滋病病毒筛查阳性率总体为6.27%，梅毒感染率为6.50%。从澡堂招募的参与者艾滋病病毒感染率（11.80%）和梅毒感染率（11.20%）最高。感染梅毒的参与者艾滋病病毒阳性筛查率最高（13.75%；95%CI OR，2.33 - 3.06）。居住在该国西南部地区（11.64%；OR = 2.76，95%CI OR 2.19 - 3.47）、年龄大于20岁（P < 0.001）、居住在该国西南部地区（OR = 2.76，95%CI 2.19 - 3.4）、过去3个月内未与女性发生性行为（OR = 1.27，95%CI 1.09 - 1.48）、最近一次肛交时未使用避孕套（OR = 1.54，95%CI 1.39 - 1.70）等因素均与艾滋病病毒检测呈阳性结果的较高可能性相关。
根据招募方式的不同，需要采取更有针对性的干预措施，以防止艾滋病病毒/艾滋病在具有不同特征和行为的男男性行为者中传播。本研究结果可为研究人员开展进一步研究以及政策制定者为中国男男性行为者制定更有效、更具战略性的干预措施提供证据。
