Baran Timothy M
J Biomed Opt. 2015 Apr;20(4):040502. doi: 10.1117/1.JBO.20.4.040502.
The axial emission and detection profiles of 1- and 2-cm cylindrical diffusing fibers based on concentration gradients of scatterers were measured. Based on these measurements, we describe a method for determination of the scatterer concentration gradient within the diffusers. Using a Monte Carlo model incorporating these concentrations, detection was simulated and found to agree with measurements. The measured and simulated detection profiles for these diffusers were found to be drastically different from those previously measured in an alternative diffuser design incorporating an end reflector. When using cylindrical diffusers as detection fibers, it is, therefore, important to understand the design of the fiber and characterize the detection behavior.
基于散射体浓度梯度,测量了1厘米和2厘米圆柱形扩散光纤的轴向发射和检测轮廓。基于这些测量结果,我们描述了一种确定扩散器内散射体浓度梯度的方法。使用包含这些浓度的蒙特卡罗模型进行模拟检测,发现与测量结果相符。发现这些扩散器的测量和模拟检测轮廓与之前在另一种包含端部反射器的扩散器设计中测量的结果有很大不同。因此,当使用圆柱形扩散器作为检测光纤时,了解光纤的设计并表征检测行为非常重要。