Ket Shara Nguyen, Bird-Lieberman Elizabeth, East James E
Translational Gastroenterology Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK.
Translational Gastroenterology Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK.
Gastrointest Endosc Clin N Am. 2015 Apr;25(2):227-42. doi: 10.1016/j.giec.2014.11.011. Epub 2015 Feb 26.
Adenoma removal prevents colorectal cancer (CRC) development. Lower adenoma detection rates correlate with increased postcolonoscopy CRC. Chromoendoscopy it is not practical for routine use. It was hoped that electronic imaging techniques would offer effective alternatives to improve detection; however, meta-analyses in average-risk patients indicate no benefit. Narrow band imaging may be of benefit for high-risk surveillance. Combining electronic imaging techniques with molecular imaging probes may highlight dysplasia at a molecular level. In future colonoscopy is likely to rely on sensitive and specific, labeled molecular probes detected by electronic endoscopic imaging to enhance detection and reduce miss rates for premalignant lesions.
腺瘤切除可预防结直肠癌（CRC）的发生。较低的腺瘤检出率与结肠镜检查后CRC发病率增加相关。色素内镜检查不适用于常规使用。人们曾希望电子成像技术能提供有效的替代方法来提高检测率；然而，对平均风险患者的荟萃分析表明并无益处。窄带成像可能对高危监测有益。将电子成像技术与分子成像探针相结合可能在分子水平上突出发育异常。未来结肠镜检查可能会依赖于通过电子内镜成像检测到的敏感且特异的标记分子探针，以提高检测率并降低癌前病变的漏诊率。
