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颈前庭诱发肌源性电位的正常值

Normal Values for Cervical Vestibular-Evoked Myogenic Potentials.

作者信息

Blakley Brian W, Wong Veronica

机构信息

*Department of Otolaryngology, †University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Otol Neurotol. 2015 Jul;36(6):1069-73. doi: 10.1097/MAO.0000000000000752.

Abstract

OBJECTIVES

To assess the variability of normal values for cervical vestibular-evoked myogenic potentials (cVEMP) testing and to provide guidance regarding which parameters should be reported for clinical practice.

STUDY DESIGN

Forty-eight normal subjects with no history of hearing loss or vestibular symptoms underwent cVEMP testing. Measurement parameters were tabulated and compared to other sets of cVEMP normal values in the literature. The literature was reviewed to assess the clinical significance of abnormal cVEMP results. The distributions of threshold and symmetry ratios for normal subjects were compared to the distributions of 90 patients who underwent cVEMP testing.

SETTING

Tertiary academic center.

RESULTS

Upper limits of 42% symmetry ratio and the range of 65 to 95 dB HL for threshold were established for our center.The quartile coefficients of dispersion were much less than 1.0 for all cVEMP parameters in the literature, suggesting that the variability in normal ranges across the literature is small. The distributions for threshold and symmetry ratio were similar between normal and patient groups. There is a lack of information in the literature regarding the impairment of function resulting from various degrees of abnormality of VEMP results.

CONCLUSIONS

Normal values for cVEMP parameters are statistically consistent in the literature. The clinical significance of abnormal values has not been validated. For clinical purposes, cVEMP "thresholds" should be reported. Reporting of other parameters is optional.

摘要

目的

评估颈前庭诱发肌源性电位(cVEMP)测试正常数值的变异性,并就临床实践中应报告哪些参数提供指导。

研究设计

48名无听力损失或前庭症状病史的正常受试者接受了cVEMP测试。将测量参数制成表格,并与文献中其他cVEMP正常数值集进行比较。回顾文献以评估cVEMP异常结果的临床意义。将正常受试者的阈值和对称率分布与90名接受cVEMP测试的患者的分布进行比较。

地点

三级学术中心。

结果

为本中心确定了对称率42%的上限以及阈值65至95 dB HL的范围。文献中所有cVEMP参数的四分位数离散系数远小于1.0,表明文献中正常范围的变异性较小。正常组和患者组之间阈值和对称率的分布相似。文献中缺乏关于VEMP结果不同程度异常导致的功能损害的信息。

结论

文献中cVEMP参数的正常数值在统计学上是一致的。异常数值的临床意义尚未得到验证。出于临床目的,应报告cVEMP“阈值”。其他参数的报告为可选。

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