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上半规管裂综合征评估与管理的当前趋势、争议及未来方向

Current Trends, Controversies, and Future Directions in the Evaluation and Management of Superior Canal Dehiscence Syndrome.

作者信息

Eberhard Kristine Elisabeth, Chari Divya A, Nakajima Hideko Heidi, Klokker Mads, Cayé-Thomasen Per, Lee Daniel J

机构信息

Department of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.

Copenhagen Hearing and Balance Centre, Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.

出版信息

Front Neurol. 2021 Apr 6;12:638574. doi: 10.3389/fneur.2021.638574. eCollection 2021.

Abstract

Patients with superior canal dehiscence syndrome (SCDS) can present with a range of auditory and/or vestibular signs and symptoms that are associated with a bony defect of the superior semicircular canal (SSC). Over the past two decades, advances in diagnostic techniques have raised the awareness of SCDS and treatment approaches have been refined to improve patient outcomes. However, a number of challenges remain. First, there is currently no standardized clinical testing algorithm for quantifying the effects of superior canal dehiscence (SCD). SCDS mimics a number of common otologic disorders and established metrics such as supranormal bone conduction thresholds and vestibular evoked myogenic potential (VEMP) measurements; although useful in certain cases, have diagnostic limitations. Second, while high-resolution computed tomography (CT) is the gold standard for the detection of SCD, a bony defect does not always result in signs and symptoms. Third, even when SCD repair is indicated, there is a lack of consensus about nomenclature to describe the SCD, ideal surgical approach, specific repair techniques, and type of materials used. Finally, there is no established algorithm in evaluation of SCDS patients who fail primary repair and may be candidates for revision surgery. Herein, we will discuss both contemporary and emerging diagnostic approaches for patients with SCDS and highlight challenges and controversies in the management of this unique patient cohort.

摘要

上半规管裂综合征(SCDS)患者可能会出现一系列与上半规管(SSC)骨缺损相关的听觉和/或前庭体征及症状。在过去二十年中,诊断技术的进步提高了对SCDS的认识,治疗方法也得到了改进以改善患者预后。然而,仍存在一些挑战。首先,目前尚无用于量化上半规管裂(SCD)影响的标准化临床测试算法。SCDS可模拟多种常见的耳科疾病以及既定指标,如超常骨导阈值和前庭诱发肌源性电位(VEMP)测量;尽管在某些情况下有用,但存在诊断局限性。其次,虽然高分辨率计算机断层扫描(CT)是检测SCD的金标准,但骨缺损并不总是导致体征和症状。第三,即使需要进行SCD修复,在描述SCD的命名法、理想的手术方法、具体的修复技术以及所用材料类型方面也缺乏共识。最后,对于初次修复失败且可能适合翻修手术的SCDS患者,尚无既定的评估算法。在此,我们将讨论SCDS患者的当代及新兴诊断方法,并强调管理这一独特患者群体时面临的挑战和争议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4055/8055857/cdfb70273cc1/fneur-12-638574-g0001.jpg

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