Vallard Alexis, Guy Jean-Baptiste, Espenel Sophie, Langrand-Escure Julien, Trone Jane-Chloé, Méry Benoîte, Moriceau Guillaume, Rivoirard Romain, de Laroche Guy, Chargari Cyrus, Magné Nicolas
Institut de cancérologie Lucien-Neuwirth, département de radiothérapie, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France.
Institut de cancérologie Lucien-Neuwirth, département d'oncologie médicale, 108 bis, avenue Albert-Raimond, BP 60008, 42271 Saint-Priest-en-Jarez cedex, France.
Bull Cancer. 2015 Jun;102(6):539-49. doi: 10.1016/j.bulcan.2015.03.001. Epub 2015 Mar 31.
The ageing of French population imposes to radiotherapists the challenge to treat older patients and to adjust their treatment. Unthinkable 30 years ago, radiation therapy concerns nowadays patients aged more than 90 years old. Oncogeriatric scales have been improved those last years without necessarily making sure that the right treatment is given to the right patient: if oncogeriatric scales use influences the final therapeutic decision, it does not define new target volumes, new doses, or new fractionation protocols. Except for some organs, there is not, for the moment, any consensus concerning geriatric population adapted treatments. This makes any therapeutic decision difficult. The present review has for objective to realise a report of the studies about favorable and unfavorable effects of radiation therapy amongst aged (>70 years old) or very aged (>90years old) population.
法国人口老龄化给放射治疗师带来了治疗老年患者并调整其治疗方案的挑战。30年前不可想象的是，如今放射治疗涉及到90岁以上的患者。近年来，老年肿瘤学量表有所改进，但不一定能确保为合适的患者提供合适的治疗：如果老年肿瘤学量表的使用会影响最终的治疗决策，它并不能定义新的靶区体积、新的剂量或新的分割方案。除了某些器官外，目前对于适合老年人群的治疗尚无共识。这使得任何治疗决策都很困难。本综述的目的是对有关放射治疗在老年（>70岁）或高龄（>90岁）人群中的有利和不利影响的研究进行报告。
