急性精神分裂症患者的多变量脑电图功率谱分析

Multivariate EEG power spectral analysis in acute schizophrenics.

作者信息

Schellenberg R, Knorr W, Beyer H, Kropf S, Schindler M, Bölsche F, Belicke B, Kondratjuk G

机构信息

Department of Pathophysiology, Medical Academy of Magdeburg, G.D.R.

出版信息

Int J Psychophysiol. 1989 Sep;8(1):85-91. doi: 10.1016/0167-8760(89)90022-6.

DOI:10.1016/0167-8760(89)90022-6

PMID:2584086

Abstract

The electroencephalogram (EEG) during information processing is influenced by specific changes in brain electrical activity. Based on the theory of disturbed information processing in schizophrenics, we analysed auditory stimulus induced EEG changes by Fast Fourier Transformation. The most important of the significant stimulation-dependent EEG power changes were measured in the 0.5-3.5 Hz and 10-13.5 Hz frequency bands in the left frontoparietal lead. In a multivariate analysis the separation of the subjects examined into acute schizophrenics and normals was incorrect in only 21% of the cases (resubstitution rate); using pi-method an error of 31% was estimated.

摘要

信息处理过程中的脑电图（EEG）受大脑电活动的特定变化影响。基于精神分裂症患者信息处理紊乱的理论，我们通过快速傅里叶变换分析了听觉刺激诱发的脑电图变化。在左额顶导联中，0.5 - 3.5赫兹和10 - 13.5赫兹频段测量到了最重要的、与刺激相关的脑电图功率显著变化。在多变量分析中，将受试对象分为急性精神分裂症患者和正常人时，只有21%的病例分类错误（再代入率）；使用π方法估计错误率为31%。