Karabag Hamza, Cakmak Erkan, Celik Bahattin, Iplikcioglu Ahmet Celal, Soran Ahmet Faruk
J Pak Med Assoc. 2014 Dec;64(12):1348-51.
To evaluate the effectiveness and safety of cervical arthroplasty and anterior cervical discectomy fusion methods.
The randomised clinical trial was conducted at the neurosurgical clinic of University of Harran, Turkey, between February 2009 and January 2010. The patients had single level disc disorder between C4-C7 levels. Before surgery, all of the patients had taken medical treatment with no improvement. Surgery was conducted with anterior approach, and disc prosthesis or polyetheretherketone cage for fusion were applied after patients were randomly divided into two groups. For preoperative and postoperative clinical evaluations Neck Disability Index and Visual Analogue Scale were used. Surgical results were evaluated according to Odom's criterion, and 'excellent' and 'good' results were accepted as successful. P<0.05 was taken as statistically significant.
Of the 42 patients in the study, 23(54.76%) were treated with Anterior Cervical Discectomy and Fusion, and 19(45.23%) with Cervical Disc Arthroplasty. There were no statistical differences between postoperative mean Visual Analogue Scale score (p<0.86) and Neck Disability Index scores (p<0.11) in the two groups. Average decrease in lordosis angle was 1.2 degree in Arthroplasty group, while it was 1 degree in the Fusion group. Postoperative adjacent segment degeneration was not detected in either group.
Anterior Cervical Discectomy and Fusion, and Cervical Disc Arthroplasty are safe and successful methods for the treatment of single level cervical disc disease. Although the latter is a relatively new technique performed with increased frequency, but its superiority is still uncertain.
评估颈椎置换术和颈椎前路椎间盘切除融合术的有效性和安全性。
该随机临床试验于2009年2月至2010年1月在土耳其哈兰大学神经外科诊所进行。患者为C4 - C7节段单节段椎间盘疾病。术前,所有患者均接受过药物治疗但无改善。采用前路手术,将患者随机分为两组后,分别应用椎间盘假体或聚醚醚酮融合器进行融合。术前和术后临床评估采用颈部功能障碍指数和视觉模拟评分。手术结果根据奥多姆标准进行评估,“优”和“良”结果视为成功。P<0.05被认为具有统计学意义。
研究中的42例患者中,23例(54.76%)接受了颈椎前路椎间盘切除融合术,19例(45.23%)接受了颈椎间盘置换术。两组术后平均视觉模拟评分(p<0.86)和颈部功能障碍指数评分(p<0.11)无统计学差异。置换术组的前凸角平均减小1.2度,融合术组为1度。两组均未检测到术后相邻节段退变。
颈椎前路椎间盘切除融合术和颈椎间盘置换术是治疗单节段颈椎间盘疾病的安全且成功的方法。尽管后者是一种应用频率增加的相对新技术,但其优越性仍不确定。