Sergeeva O V, Sergiev P V, Bogdanov A A, Dontsova O A
Mol Biol (Mosk). 2014 Jul-Aug;48(4):543-60.
Ribosome is a macromolecular complex, which is responsible for protein biosynthesis. Two bacterial ribosomal subunits contain more than 4000 RNA nucleotides and 50 proteins. Ribosome assembly is a complicated multi-step process, vitally important for cell. In this review we summarised present-day conceptions about the mechanism of the bacterial ribosome assembly in the cell and in vitro model systems. Some details of the assembly of this machinery are still-unknown.
核糖体是一种大分子复合物，负责蛋白质的生物合成。两个细菌核糖体亚基包含4000多个核糖核苷酸和50种蛋白质。核糖体组装是一个复杂的多步骤过程，对细胞至关重要。在本综述中，我们总结了目前关于细菌核糖体在细胞内和体外模型系统中组装机制的概念。该机制的一些细节仍然未知。
