Hamir A N, Reef V B
New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
J Comp Pathol. 1989 Oct;101(3):317-26. doi: 10.1016/0021-9975(89)90041-8.
Gross and histopathological findings in a 9-year-old horse implanted with permanent transvenous pacing cardiac catheters, 18 and 34 months before its death, are described. Lesions consisting of extensive fibrino-haemorrhagic thrombi with large numbers of bacterial colonies were present along the electrode wires and on mural and valvular endocardial surfaces of the right heart. There was a locally extensive area of suppurative endocarditis around the attachment site of the atrial electrode, which was loosely attached by a thin band of membranous tissue to the endocardium. The ventricular electrode was firmly embedded in the myocardium and was surrounded by a dense area of fibrous connective tissue in which multifocal mineralized areas were seen. Histologically, there was evidence of terminal bacteraemia. The observed lesions are discussed with respect to findings in man and other animals with similar cardiac implants.
描述了一匹9岁马在死亡前18个月和34个月植入永久性经静脉起搏心脏导管后的大体和组织病理学发现。沿电极导线以及右心壁和瓣膜心内膜表面存在由大量细菌菌落组成的广泛纤维蛋白 - 出血性血栓病变。心房电极附着部位周围有局部广泛的化脓性心内膜炎区域，该电极通过一条薄的膜状组织带松散地附着于心内膜。心室电极牢固地嵌入心肌，周围是致密的纤维结缔组织区域，其中可见多灶性矿化区域。组织学上，有终末期菌血症的证据。结合人类和其他植入类似心脏装置的动物的研究结果，对观察到的病变进行了讨论。
