Husein-ElAhmed Husein
Department of Dermatology, Infanta Margarita Hospital, Córdoba, Spain.
Dermatol Ther. 2015 May-Jun;28(3):166-72. doi: 10.1111/dth.12231. Epub 2015 Apr 6.
Acne vulgaris is a very common condition affecting up of 93% of adolescents. Although rare, this disease may persist in adulthood. In adult women with acne (those older than 25 years old), this condition is particularly relevant because of the refractory to conventional therapies, which makes acne a challenge for dermatologists in this group of patients. In order to its potential risk for chronicity and the involvement of visible anatomical sites such as face and upper torso, acne has been associated with a wide spectrum of psychological and social dysfunction such as depression, anxiety, suicidal ideation, somatization, and social inhibition. In particular, adult women with acne have been shown to be adversely impacted by the effect of acne on their quality of life. For the last four decades, dermatologists have used hormonal therapies for the management of acne vulgaris in adult women, which are considered a rational choice given the severity and chronicity of this condition in this group of patients. The aim of this work is to review the hormonal drugs for management of acne.
寻常痤疮是一种非常常见的病症，影响着高达93%的青少年。虽然罕见，但这种疾病可能会持续到成年期。在成年女性痤疮患者（年龄超过25岁）中，由于对传统疗法难治，这种情况尤为突出，这使得痤疮成为皮肤科医生在这类患者群体中面临的一个挑战。鉴于痤疮有慢性化的潜在风险以及面部和上半身等可见解剖部位受累，痤疮已与广泛的心理和社会功能障碍相关联，如抑郁、焦虑、自杀意念、躯体化和社交抑制。特别是，成年女性痤疮患者已被证明会因其痤疮对生活质量的影响而受到不利影响。在过去的四十年里，皮肤科医生一直使用激素疗法来治疗成年女性的寻常痤疮，考虑到这类患者病情的严重性和慢性化，这被认为是一种合理的选择。这项工作的目的是综述用于治疗痤疮的激素药物。
