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[在缺铁性贫血发展背景下给予小鼠高分散铁粉后其器官和血液中巯基水平的变化]

[Changes in the level of sulfhydryl groups in the organs and blood of mice administered a highly dispersed iron powder against a background of developing anemia].

作者信息

Ivanenko G F, Fedorov Iu I, Burlakova E B

出版信息

Izv Akad Nauk SSSR Biol. 1989 Sep-Oct(5):772-6.

PMID:2584535
Abstract

Alimentary iron deficiency causes significant changes in thiol content: the increase in the content of protein sulfhydryl groups in organs at late stages and the decrease in that of non-protein sulfhydryl groups at early stages of experiment. A preliminary introduction of 10 mg/kg fine iron powder (FIP) into animals fed iron-free food leads to the decrease in sulfhydryl group content in organs and blood of experimental mice. The decrease in sulfhydryl group content at FIP introduction might be connected with changes in activity of glutathione-dependent enzymes.

摘要

营养性缺铁会导致巯基含量发生显著变化

在实验后期器官中蛋白质巯基含量增加,而在实验早期非蛋白质巯基含量减少。给食用无铁食物的动物预先引入10mg/kg的细铁粉(FIP)会导致实验小鼠器官和血液中巯基含量降低。引入FIP后巯基含量的降低可能与谷胱甘肽依赖性酶活性的变化有关。

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