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无应答者存在什么问题?在丹麦健康与发病率调查中对应答者和无应答者进行的一项为期12年的随访研究中与酒精、药物和吸烟相关的死亡率和发病率。

What is wrong with non-respondents? Alcohol-, drug- and smoking-related mortality and morbidity in a 12-year follow-up study of respondents and non-respondents in the Danish Health and Morbidity Survey.

作者信息

Christensen Anne Illemann, Ekholm Ola, Gray Linsay, Glümer Charlotte, Juel Knud

机构信息

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.

出版信息

Addiction. 2015 Sep;110(9):1505-12. doi: 10.1111/add.12939. Epub 2015 Jun 2.

Abstract

AIM

Response rates in health surveys have diminished over the last two decades, making it difficult to obtain reliable information on health and health-related risk factors in different population groups. This study compared cause-specific mortality and morbidity among survey respondents and different types of non-respondents to estimate alcohol-, drug- and smoking-related mortality and morbidity among non-respondents.

DESIGN

Prospective follow-up study of respondents and non-respondents in two cross-sectional health surveys.

SETTING

Denmark.

PARTICIPANTS

A total sample of 39 540 Danish citizens aged 16 years or older.

MEASUREMENTS

Register-based information on cause-specific mortality and morbidity at the individual level was obtained for respondents (n = 28 072) and different types of non-respondents (refusals n = 8954; illness/disabled n = 731, uncontactable n = 1593). Cox proportional hazards models were used to examine differences in alcohol-, drug- and smoking-related mortality and morbidity, respectively, in a 12-year follow-up period.

FINDINGS

Overall, non-response was associated with a significantly increased hazard ratio (HR) of 1.56 [95% confidence interval (CI) = 1.36-1.78] for alcohol-related morbidity, 1.88 (95% CI = 1.38-2.57) for alcohol-related mortality, 1.55 (95% CI = 1.27-1.88) for drug-related morbidity, 3.04 (95% CI = 1.57-5.89) for drug-related mortality and 1.15 (95% CI = 1.03-1.29) for smoking-related morbidity. The hazard ratio for smoking-related mortality also tended to be higher among non-respondents compared with respondents, although no significant association was evident (HR = 1.14; 95% CI = 0.95-1.36). Uncontactable and ill/disabled non-respondents generally had a higher hazard ratio of alcohol-, drug- and smoking-related mortality and morbidity compared with refusal non-respondents.

CONCLUSION

Health survey non-respondents in Denmark have an increased hazard ratio of alcohol-, drug- and smoking-related mortality and morbidity compared with respondents, which may indicate more unfavourable health behaviours among non-respondents.

摘要

目的

在过去二十年中,健康调查的回应率有所下降,这使得获取不同人群健康及健康相关风险因素的可靠信息变得困难。本研究比较了调查受访者与不同类型未受访者之间特定病因的死亡率和发病率,以估计未受访者中与酒精、药物和吸烟相关的死亡率和发病率。

设计

对两项横断面健康调查中的受访者和未受访者进行前瞻性随访研究。

地点

丹麦。

参与者

总共39540名年龄在16岁及以上的丹麦公民。

测量

获取了受访者(n = 28072)和不同类型未受访者(拒绝者n = 8954;患病/残疾者n = 731,无法联系者n = 1593)基于登记的个体层面特定病因死亡率和发病率信息。使用Cox比例风险模型分别在12年随访期内检验与酒精、药物和吸烟相关的死亡率和发病率的差异。

结果

总体而言,未回应与酒精相关发病率的风险比(HR)显著增加1.56[95%置信区间(CI)= 1.36 - 1.78],酒精相关死亡率为1.88(95%CI = 1.38 - 2.57),药物相关发病率为1.55(95%CI = 1.27 - 1.88),药物相关死亡率为3.04(95%CI = 1.57 - 5.89),吸烟相关发病率为1.15(95%CI = 1.03 - 1.29)。与受访者相比,未受访者中吸烟相关死亡率的风险比也往往更高,尽管没有明显的显著关联(HR = 1.14;95%CI = 0.95 - 1.36)。与拒绝未受访者相比,无法联系和患病/残疾的未受访者在酒精、药物和吸烟相关死亡率和发病率方面的风险比通常更高。

结论

丹麦健康调查中的未受访者与受访者相比,在酒精、药物和吸烟相关死亡率和发病率方面的风险比增加,这可能表明未受访者中存在更不利的健康行为。

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