National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Gastrounit, Medical Division, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Addiction. 2017 Oct;112(10):1754-1764. doi: 10.1111/add.13875. Epub 2017 Jul 4.
We investigated the association between weekly alcohol consumption and binge drinking and the risk of unemployment, sickness absence and disability pension.
Prospective register-based cohort study.
Denmark.
A sample of 17 690 men and women, aged 18-60 years from the Danish Health and Morbidity Survey in 2000, 2005 and 2010 participated in the study. Participants worked the entire year prior to baseline.
Administrative registers were used to obtain information on unemployment, sickness absence and disability pension during a 5-year follow-up period. Data were analysed by multivariate Cox regression model with random effect (frailty) adjusted for cohabitation status, educational level, Charlson comorbidity index, smoking habits, calendar year and geographic region.
Among males, adjusted hazards ratios (HR) of unemployment were 1.24 (95% CI 1.05-1.46, P = 0.01), 1.28 (95% CI 1.04-1.59, P =0.02) and 1.48 (95% CI 1.21-1.81, P = 0.00) respectively, for abstainers and those with alcohol consumption of 21-27 and ≥ 28 drinks per week when compared with individuals who had 1-13 drinks per week. Corresponding HRs for sickness absence were 1.16 (95% CI 1.02-1.33, P = 0.03), 1.02 (95% CI 0.85-1.23, P = 0.84), and 1.23 (95 % CI 1.04-1.46, P = 0.02). Male abstainers had increased HR for subsequently receiving disability pension. Female abstainers had increased HR of unemployment, sickness absence and disability pension compared to women with moderate alcohol consumption. Binge drinking was associated with higher HR of unemployment compared to non-binge drinking in women: HR of 1.21 (95 % CI 1.03-1.41, P = 0.02).
In Danish men aged 18-60, alcohol abstinence and heavy consumption is associated with increased subsequent risk of unemployment and sickness absence compared with low consumption. In Danish women abstainers have increased risk of unemployment, sickness absence and disability pension, while binge drinkers are more likely to become unemployed subsequently.
我们研究了每周饮酒量和狂饮与失业、病假和残疾养老金风险之间的关联。
前瞻性基于登记的队列研究。
丹麦。
来自 2000 年、2005 年和 2010 年丹麦健康和发病率调查的 17690 名年龄在 18-60 岁之间的男性和女性参加了这项研究。参与者在基线前的整个一年都在工作。
行政登记册用于在 5 年的随访期间获得失业、病假和残疾养老金方面的信息。通过具有随机效应（脆弱性）调整的多变量 Cox 回归模型对数据进行分析，调整因素包括同居状况、教育程度、Charlson 合并症指数、吸烟习惯、日历年份和地理位置。
在男性中，与每周饮酒 1-13 次的个体相比，不饮酒者和每周饮酒 21-27 次和≥28 次的个体的失业风险调整后的危害比（HR）分别为 1.24（95%CI 1.05-1.46，P=0.01）、1.28（95%CI 1.04-1.59，P=0.02）和 1.48（95%CI 1.21-1.81，P=0.00）。相应的病假风险调整 HR 分别为 1.16（95%CI 1.02-1.33，P=0.03）、1.02（95%CI 0.85-1.23，P=0.84）和 1.23（95%CI 1.04-1.46，P=0.02）。男性不饮酒者随后获得残疾养老金的风险调整 HR 增加。与中度饮酒的女性相比，女性不饮酒者的失业、病假和残疾养老金风险调整 HR 增加。与非狂饮相比，女性狂饮与更高的失业风险调整 HR 相关：HR 为 1.21（95%CI 1.03-1.41，P=0.02）。
在丹麦 18-60 岁的男性中，与低饮酒量相比，酒精戒断和大量饮酒与随后失业和病假风险增加相关。在丹麦女性中，不饮酒者失业、病假和残疾养老金的风险增加，而狂饮者随后更有可能失业。
