Pope Jason E, Falowski Steven, Deer Tim R
Center for Pain Relief, Inc., 400 Court Street, Charleston, WV 25301, USA.
Expert Rev Med Devices. 2015 Jul;12(4):431-7. doi: 10.1586/17434440.2015.1026805. Epub 2015 Apr 6.
In recent years, software development has been key to the next generation of neuromodulation devices. In this review, we will describe the new strategies for electrical waveform delivery for spinal cord stimulation. A systematic literature review was performed using bibliographic databases, limited to the English language and human data, between 2010 and 2014. The literature search yielded three articles on burst stimulation and four articles on high-frequency stimulation. High-frequency and burst stimulation may offer advantages over tonic stimulation, as data suggest improved patient tolerance, comparable increase in function and possible success with a subset of patients refractory to tonic spinal cord stimulation. High-frequency and burst stimulation are new ways to deliver energy to the spinal cord that may offer advantages over tonic stimulation. These may offer new salvage strategies to mitigate spinal cord stimulation failure and improve cost-effectiveness by reducing explant rate.
近年来，软件开发对于下一代神经调节设备至关重要。在本综述中，我们将描述脊髓刺激中电波形传递的新策略。我们使用书目数据库进行了一项系统的文献综述，限于2010年至2014年期间的英文文献和人体数据。文献检索得出了三篇关于爆发式刺激的文章和四篇关于高频刺激的文章。高频和爆发式刺激可能比强直性刺激具有优势，因为数据表明患者耐受性有所提高，功能有相当程度的增加，并且对于一部分对强直性脊髓刺激无效的患者可能取得成功。高频和爆发式刺激是向脊髓传递能量的新方式，可能比强直性刺激具有优势。这些可能提供新的挽救策略，以减轻脊髓刺激失败，并通过降低植入物取出率提高成本效益。
