Alkhachroum Ayham M, Kazzaz Nayef
Department of Medicine, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Department of Medicine, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
J Community Hosp Intern Med Perspect. 2015 Apr 1;5(2):26645. doi: 10.3402/jchimp.v5.26645. eCollection 2015.
A patient with a known biopsy of polyarteritis nodosa diagnosis presented with cyclic fevers, acute kidney injury, and progression of rash from macular to pustular, worsening despite being on antibiotics, without evidence of infection on multiple cultures. The patient had a pathological diagnosis from a skin biopsy of acute generalized exanthematous pustulosis syndrome, with a total resolution of rash, fevers, and acute kidney injury on treatment with pulse steroids.
一名已知诊断为结节性多动脉炎且已进行活检的患者出现周期性发热、急性肾损伤，皮疹从斑疹进展为脓疱疹，尽管使用了抗生素但病情仍在恶化，多次培养均无感染证据。该患者经皮肤活检病理诊断为急性泛发性脓疱病综合征，经脉冲类固醇治疗后皮疹、发热和急性肾损伤完全消退。
