Berkani K, Dimet J
Service de pneumologie, centre hospitalier départemental Les Oudairies, 85925 La Roche-sur-Yon cedex 9, France.
Unité de recherche clinique, centre hospitalier départemental Les Oudairies, 85925 La Roche-sur-Yon cedex 9, France.
Rev Mal Respir. 2015 Mar;32(3):249-55. doi: 10.1016/j.rmr.2014.01.012. Epub 2014 Apr 18.
Compliance with continuous positive pressure treatment (CPAP) is a determining factor in the management of the obstructive sleep apnea syndrome (OSAS). Long-term compliance has been poorly studied.
The probability of long-term continuation of CPAP was evaluated retrospectively by an analysis of survival in 252 patients treated by CPAP after a screening of 472 patients during the years 2002 and 2003.
Twenty-eight patients fulfilling the criteria for CPAP immediately refused the treatment. The mean follow-up for the 252 treated patients was 76.9±46.4 months, with 38 patients having died and 75 having discontinued treatment during the period. The 136 patients who continued treatment used CPAP for a mean of 7.4±1.6hours daily. The probability of continuing treatment was 71% at 5 years and 68% at 10 years. The severity of OSAS was a predictive factor for long-term CPAP compliance, with a 10-year compliance of 82% in patients having an apnoea/hypopnoea index >60, versus 68% with an index between 30-60 and 44% with an index <30.
Long-term CPAP treatment is globally well accepted, with a 68% probability of continuing treatment for 10 years, particularly in the most severely affected patients. Long-term daily compliance is very satisfactory.
持续气道正压通气治疗（CPAP）的依从性是阻塞性睡眠呼吸暂停综合征（OSAS）管理中的一个决定性因素。长期依从性的研究较少。
通过对2002年和2003年期间472例患者进行筛查后接受CPAP治疗的252例患者的生存分析，回顾性评估CPAP长期持续使用的可能性。
28例符合CPAP标准的患者立即拒绝治疗。252例接受治疗患者的平均随访时间为76.9±46.4个月，在此期间38例患者死亡，75例患者停止治疗。136例继续治疗的患者每天使用CPAP的平均时间为7.4±1.6小时。5年时继续治疗的概率为71%，10年时为68%。OSAS的严重程度是长期CPAP依从性的一个预测因素，呼吸暂停/低通气指数>60的患者10年依从性为82%，指数在30 - 60之间的患者为68%，指数<30的患者为44%。
长期CPAP治疗总体上被广泛接受，10年继续治疗的概率为68%，特别是在受影响最严重的患者中。长期每日依从性非常令人满意。
