Challita S, Guerder A, Charpentier M-C, Daher M, Giraud F, Roche N
Service de pneumologie et soins intensifs respiratoires, groupe hospitalier Cochin Broca Hôtel-Dieu, université Paris Descartes, AP-HP, Paris, France.
Service d'anatomopathologie, groupe hospitalier Cochin Broca Hôtel-Dieu, université Paris Descartes, AP-HP, Paris, France.
Rev Mal Respir. 2015 Mar;32(3):271-4. doi: 10.1016/j.rmr.2014.06.029. Epub 2014 Aug 6.
The majority of pleural and peritoneal mesotheliomas are linked to asbestos exposure but, in around 20% of cases, no history of such exposure is found. Periodic disease is associated with recurrent serositis, which could favor the development of mesothelioma.
We report a case of pleural mesothelioma in a 50-year-old Lebanese woman, with no detectable exposure to asbestos but suffering from periodic disease (familial Mediterranean fever) with recurrent episodes of serositis.
Many cases of peritoneal mesothelioma in patients with FMF are reported in the literature. This is the second reported case of pleural mesothelioma associated with periodic disease. Because of the low incidence of both diseases, further publications are required to support the hypothesis of a causal link. It is important, therefore, that all cases of an association of periodic disease and mesothelioma are reported.
大多数胸膜和腹膜间皮瘤与接触石棉有关，但在约20%的病例中，未发现此类接触史。周期性疾病与复发性浆膜炎相关，这可能有利于间皮瘤的发生。
我们报告一例50岁黎巴嫩女性的胸膜间皮瘤病例，该患者未检测到接触石棉，但患有周期性疾病（家族性地中海热）且有复发性浆膜炎发作。
文献中报道了许多家族性地中海热患者发生腹膜间皮瘤的病例。这是第二例报道的与周期性疾病相关的胸膜间皮瘤病例。由于这两种疾病的发病率都很低，需要更多的出版物来支持因果关系的假设。因此，报告所有周期性疾病与间皮瘤相关的病例很重要。
