Doggui Radhouene, Ingrand Jacques
Laboratoire de surveillance et épidémiologie nutritionnelles en Tunisie (Surven), Institut national de nutrition et de technologie alimentaire, Tunis, Tunisie.
Unité de formation continue Acorata, Sajas, France.
Ann Biol Clin (Paris). 2015 Mar-Apr;73(2):212-20. doi: 10.1684/abc.2015.1033.
Tri-iodothyronine (T3) is the active form of thyroid hormone at the nuclear cell level. About 80% of tri-iodothyronine is produced by peripheral deiodination of thyroxine. The determination of the free form of this hormone is useful for the diagnosis and the follow-up of hyperthyroidism. In routine clinical laboratories, immunoassays remain the most used technics. After recalling the main points related to the physiological data, the authors point out the possible errors during the analytical steps of the assay.
三碘甲状腺原氨酸(T3)在细胞核水平是甲状腺激素的活性形式。约80%的三碘甲状腺原氨酸由甲状腺素的外周脱碘产生。测定这种激素的游离形式对甲状腺功能亢进症的诊断和随访有用。在常规临床实验室中,免疫测定仍然是最常用的技术。在回顾了与生理数据相关的要点后,作者指出了该检测分析步骤中可能出现的误差。