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PET-CT检查的患者辐射剂量。

Patient doses from PET-CT procedures.

作者信息

Avramova-Cholakova S, Ivanova S, Petrova E, Garcheva M, Vassileva J

机构信息

National Centre of Radiobiology and Radiation Protection, Sofia, Bulgaria

University Multiprofile Hospital for Active Treatment 'St Marina', Varna, Bulgaria.

出版信息

Radiat Prot Dosimetry. 2015 Jul;165(1-4):430-3. doi: 10.1093/rpd/ncv128. Epub 2015 Apr 5.

Abstract

Positron emission tomography (PET) was installed for the first time in Bulgaria in 2009, and nowadays two hybrid PET-computed tomography (CT) systems are in operation. The aim of this work is to estimate patient doses from PET-CT procedures and to explore potential for optimisation. Data were retrospectively collected for 50 patients examined with the system Philips Gemini TF and for 58 patients examined with the system GE Discovery 600. Whole-body examinations with radiopharmaceutical (18)F-2-fluoro-2-deoxy-D-glucose (FDG) were performed on all patients. Patient effective doses from the CT component of the examination were calculated with CT Expo software and compared with doses estimated applying the National Radiological Protection Board (NRPB) conversion coefficients. Effective doses from the PET component were calculated applying the ICRP 80 conversion coefficients. For the first system, average effective doses from CT component were 8.0 and 8.9 mSv, applying CT Expo and NRPB coefficients, respectively, and 4.9 mSv from PET component. For the second system, the corresponding values were 7.8, 8.7 and 5.9 mSv. These results for patient effective doses are relatively lower or comparable to other similar surveys. Reasons for the observed differences are analysed and presented.

摘要

正电子发射断层扫描(PET)于2009年首次在保加利亚安装,如今有两台PET-计算机断层扫描(CT)混合系统在运行。这项工作的目的是估算PET-CT检查给患者带来的剂量,并探索优化的潜力。回顾性收集了使用飞利浦Gemini TF系统检查的50例患者以及使用GE Discovery 600系统检查的58例患者的数据。所有患者均使用放射性药物(18)F-2-氟-2-脱氧-D-葡萄糖(FDG)进行了全身检查。使用CT Expo软件计算检查中CT部分给患者带来的有效剂量,并与应用国家放射防护委员会(NRPB)转换系数估算的剂量进行比较。使用国际放射防护委员会(ICRP)80号出版物的转换系数计算PET部分的有效剂量。对于第一个系统,应用CT Expo和NRPB系数时,CT部分的平均有效剂量分别为8.0和8.9 mSv,PET部分为4.9 mSv。对于第二个系统,相应的值分别为7.8、8.7和5.9 mSv。这些患者有效剂量的结果相对较低,或与其他类似调查结果相当。分析并阐述了观察到的差异的原因。

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