Miyahara Takuya, Shigematsu Kunihiro, Nishiyama Ayako, Hashimoto Takuya, Hoshina Katsuyuki, Watanabe Toshiaki
Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Tokyo, Japan.
Ann Vasc Dis. 2015;8(1):14-20. doi: 10.3400/avd.oa.14-00119. Epub 2015 Feb 16.
This study was designed to investigate our long-term experience with combined iliac endovascular therapy (EVT) and infrainguinal bypass to treat critical limb ischemia (CLI) and compare outcomes to those of patients who underwent surgery for aortoiliac lesions.
From April 2000 to June 2013, 57 patients (58 limbs) underwent an infrainguinal bypass combined with aortoiliac reconstruction to treat CLI. Eighteen limbs were treated by bypass alone and 8 limbs were treated by bypass with EVT for aortoiliac lesions (Bypass group). Thirty-two limbs were subjected to EVT alone for iliac lesions (EVT group).
Preoperative limb ischemia was more severe in the EVT group. There were no significant differences in major procedure-related complications (χ(2) test, P = 0.853), systemic complications (P = 0.853), and mortality (P = 0.916) between the 2 groups. The limb salvage rates were 92% at 1, 3, and 5 years in the Bypass group and 93% at 1, 3, and 5 years in the EVT group, with no significant difference observed between the groups (Kaplan-Meier, log-rank test, P = 0.616).
Infrainguinal surgical reconstruction combined with an iliac EVT is an acceptable strategy for managing patients with CLI.
本研究旨在探讨我们采用髂血管腔内治疗(EVT)联合股腘动脉旁路移植术治疗严重肢体缺血(CLI)的长期经验,并将结果与接受主髂动脉病变手术的患者进行比较。
2000年4月至2013年6月,57例患者(58条肢体)接受了股腘动脉旁路移植术联合主髂动脉重建术以治疗CLI。18条肢体仅接受旁路移植术治疗,8条肢体接受旁路移植术联合主髂动脉病变的EVT治疗(旁路移植组)。32条肢体仅接受髂动脉病变的EVT治疗(EVT组)。
EVT组术前肢体缺血更严重。两组在主要手术相关并发症(χ²检验,P = 0.853)、全身并发症(P = 0.853)和死亡率(P = 0.916)方面无显著差异。旁路移植组1年、3年和5年的肢体挽救率分别为92%,EVT组为93%,两组间无显著差异(Kaplan-Meier法,对数秩检验,P = 0.616)。
股腘动脉手术重建联合髂动脉EVT是治疗CLI患者的一种可接受的策略。