Cantarero-Arévalo Lourdes, Holstein Bjørn E, Andersen Anette, Kristiansen Maria, Hansen Ebba H
Department of Pharmacy, Section for Social and Clinical Pharmacy. Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2.2100, Copenhagen, Denmark.
National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
J Pharm Policy Pract. 2014 Jan 22;7:1. doi: 10.1186/2052-3211-7-1. eCollection 2014.
The aims of the study were to examine the association between immigrant background and medicine use for headache and stomach-ache among adolescents, and whether symptoms of headache and stomach-ache could explain the differences in medicine use.
We used data from the Danish contribution to the WHO-affiliated international cross-sectional survey Health Behaviour in School-aged Children (HBSC) in 2006. Among boys, a total of 4170 ethnic Danes, 244 descendants of immigrants, and 224 immigrants participated. Among girls, 4310 ethnic Danes, 264 descendants of immigrants, and 232 immigrants were included. The associations between migrant background and medicine use for headache and stomach-ache by means of multilevel multivariate logistic regression analyses adjusted for age group, symptoms and the clustering effect of school and stratified by sex due to interactions.
Among boys, the risk of medicine use for stomach-ache was higher for immigrants (odds ratio (OR), 1.54; 95% confidence intervals (CI), 0.99-2.44)) and descendants (OR, 1.97 (1.33-2.94)) compared to ethnic Danes. Similar associations were found for use of medicine for stomach-ache for immigrant girls (OR, 1.55 (1.12-2.15) and use of medicine for headache among boys (immigrants (OR, 1.36 (1.02-1.97 and descendants (1.48 (1.12-1.97)). Symptoms of aches were all independently associated with medicine use. After adjusting for these factors the association between immigrant background and medicine use attenuated slightly.
Among adolescents in Denmark, the risk of medicine use for headache and stomach-ache was higher for immigrants and descendants as compared to ethnic Danes, with the exception of medicine use for headache among girls.
本研究旨在探讨青少年移民背景与头痛和胃痛用药之间的关联,以及头痛和胃痛症状是否能够解释用药差异。
我们使用了丹麦对2006年世界卫生组织附属国际横断面调查“学龄儿童健康行为”(HBSC)的贡献数据。在男孩中,共有4170名丹麦族裔、244名移民后代和224名移民参与。在女孩中,纳入了4310名丹麦族裔、264名移民后代和232名移民。通过多水平多变量逻辑回归分析,对年龄组、症状以及学校的聚类效应进行调整,并因交互作用按性别分层,分析移民背景与头痛和胃痛用药之间的关联。
在男孩中,与丹麦族裔相比,移民(比值比(OR)为1.54;95%置信区间(CI)为0.99 - 2.44)和移民后代(OR为1.97(1.33 - 2.94))胃痛用药风险更高。移民女孩胃痛用药(OR为1.55(1.12 - 2.15))以及男孩头痛用药(移民(OR为1.36(1.02 - 1.97))和移民后代(1.48(1.12 - 1.97))也发现了类似关联。疼痛症状均与用药独立相关。在调整这些因素后,移民背景与用药之间的关联略有减弱。
在丹麦青少年中,与丹麦族裔相比,移民和移民后代头痛和胃痛用药风险更高,但女孩头痛用药情况除外。