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发展中国家法洛四联症矫正手术后术中拔管的可行性与安全性:病例系列报告

Feasibility and safety of on table extubation after corrective surgical repair of tetralogy of Fallot in a developing country: a case series.

作者信息

Akhtar Mohammad Irfan, Hamid Mohammad, Minai Fauzia, Rehman Naveed

机构信息

Department of Anesthesia, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Ann Card Anaesth. 2015 Apr-Jun;18(2):237-41. doi: 10.4103/0971-9784.154490.

Abstract

Fast-track extubation is an established safe practice in pediatric congenital heart disease (CHD) surgical patients. On table extubation (OTE) in acyanotic CHD surgical patients is well established with validated safety profile. This practice is not yet reported in tetralogy of Fallot (TOF) cardiac surgical repair patients in developing countries. Evidence suggests that TOF total correction patients should be extubated early, as positive pressure ventilation has a negative impact on right ventricular function and the overall increase in post-TOF repair complications such as low cardiac output state and arrhythmias. The objective of the case series was to determine the safety and feasibility of OTE in elective TOF total correction cardiac surgical patients with an integrated team approach. To the best of our knowledge, this is the first reported case series. A total of 8 elective male and female TOF patients were included. Standard anesthetic, surgical and perfusion techniques were used in these procedures. All patients were extubated in the operating room safely without any complications with the exception of one patient who continued to bleed for 3 h of postextubation at 2-3 ml/kg/h which was managed with transfusion of fresh frozen plasma at 15 mL/kg, packed red blood cells 10 mL/kg and bolus of transamine at 20 mg/kg. Apart from better surgical and bypass techniques, the most important factor leading to successful OTE was an excellent analgesia. On the basis of the case series, it is suggested to extubate selected TOF cardiac surgery repair patients on table safely with integrated multidisciplinary approach.

摘要

快速拔管是小儿先天性心脏病(CHD)手术患者中已确立的安全做法。非紫绀型CHD手术患者的术中拔管(OTE)已得到充分确立,且安全性已得到验证。在发展中国家,法洛四联症(TOF)心脏手术修复患者中尚未有这种做法的报道。有证据表明,TOF根治术患者应尽早拔管,因为正压通气会对右心室功能产生负面影响,并会增加TOF修复术后诸如低心排血量状态和心律失常等并发症的总体发生率。该病例系列的目的是通过综合团队方法确定OTE在择期TOF根治性心脏手术患者中的安全性和可行性。据我们所知,这是首次报道的病例系列。共纳入8例择期TOF手术的男性和女性患者。这些手术采用了标准的麻醉、手术和灌注技术。所有患者均在手术室安全拔管,无一例出现并发症,但有1例患者在拔管后持续出血3小时,出血量为2 - 3 ml/(kg·h),通过输注15 mL/kg的新鲜冰冻血浆、10 mL/kg的浓缩红细胞和20 mg/kg的氨甲环酸进行处理。除了更好的手术和体外循环技术外,导致OTE成功的最重要因素是出色的镇痛效果。基于该病例系列,建议采用多学科综合方法,在术中安全地为选定的TOF心脏手术修复患者拔管。

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本文引用的文献

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