Fukunishi Takuma, Oka Norihiko, Yoshii Takeshi, Kobayashi Kensuke, Inoue Nobuyuki, Horai Tetsuya, Kitamura Tadashi, Okamoto Hirotsugu, Miyaji Kagami
Department of Cardiovascular Surgery, Kitasato University School of Medicine.
Department of Anesthesiology, Kitasato University School of Medicine.
Int Heart J. 2018 Jan 27;59(1):94-98. doi: 10.1536/ihj.16-630. Epub 2018 Jan 15.
Early extubation in the operating room after congenital open-heart surgery is feasible, but extubation in the intensive care unit after the operation remains common practice at many institutions. The purpose of this study was to evaluate retrospectively the adequacy of our early-extubation strategy and exclusion criteria through analysis based on the Risk Adjustment in Congenital Heart Surgery method (RACHS-1).This retrospective analysis included 359 cases requiring cardiopulmonary bypass (male, 195; female, 164; weight > 3.0 kg; aged 1 month to 18 years). Neonates and preoperatively intubated patients were excluded. Other exclusion criteria included severe preoperative pulmonary hypertension, high-dose catecholamine requirement after cardiopulmonary bypass, delayed sternal closure, laryngomalacia, serious bleeding, and delayed awakening. The early-extubation rates were compared between age groups and RACHS-1 classes.Overall, 83% of cases (298/359) were extubated in the operating room, classified by RACHS-1 categories as follows: 1, 59/59 (100%); 2, 164/200 (84%); 3, 61/78 (78%); and 4-6, 10/22 (45%). The early extubation rate in categories 1-3 (86%, 288/337) was significantly higher than for categories 4-6 (45.5%, 10/22) (P < 0.001). Because they met one of the exclusion criteria, 61 patients (17%) were not extubated in the operating room. Eight patients (2.7%) required re-intubation after early extubation in the operating room, and longer operation time was significantly associated with re-intubation (P < 0.001).Extubation in the operating room after congenital open-heart surgery was feasible based on our criteria, especially for patients in the low RACHS-1 categories, and involves a very low rate of re-intubation.
先天性心脏直视手术后在手术室早期拔管是可行的,但术后在重症监护病房拔管在许多机构仍是常见做法。本研究的目的是通过基于先天性心脏病手术风险调整方法(RACHS-1)的分析,回顾性评估我们早期拔管策略和排除标准的充分性。这项回顾性分析纳入了359例需要体外循环的病例(男性195例;女性164例;体重>3.0 kg;年龄1个月至18岁)。新生儿和术前已插管的患者被排除。其他排除标准包括术前严重肺动脉高压、体外循环后需要高剂量儿茶酚胺、胸骨延迟闭合、喉软化、严重出血和苏醒延迟。比较了各年龄组和RACHS-1分级之间的早期拔管率。总体而言,83%的病例(298/359)在手术室拔管,按RACHS-1分级分类如下:1级,59/59(100%);2级,164/200(84%);3级,61/78(78%);4 - 6级,10/22(45%)。1 - 3级的早期拔管率(86%,288/337)显著高于4 - 6级(45.5%,10/22)(P<0.001)。由于符合一项排除标准,61例患者(17%)未在手术室拔管。8例患者(2.7%)在手术室早期拔管后需要重新插管,手术时间较长与重新插管显著相关(P<0.001)。根据我们的标准,先天性心脏直视手术后在手术室拔管是可行的,尤其是对于低RACHS-1分级的患者,且重新插管率非常低。