The ethics of global clinical trials: In developing countries, participation in clinical trials is sometimes the only way to access medical treatment. What should be done to avoid exploitation of disadvantaged populations?
作者信息
Weigmann Katrin
机构信息
Oldenburg, Germany.
出版信息
EMBO Rep. 2015 May;16(5):566-70. doi: 10.15252/embr.201540398. Epub 2015 Apr 7.
Abstract
摘要
相似文献
1
The ethics of global clinical trials: In developing countries, participation in clinical trials is sometimes the only way to access medical treatment. What should be done to avoid exploitation of disadvantaged populations?
EMBO Rep. 2015 May;16(5):566-70. doi: 10.15252/embr.201540398. Epub 2015 Apr 7.
2
Undue inducement in clinical research in developing countries: is it a worry?
Lancet. 2005;366(9482):336-40. doi: 10.1016/S0140-6736(05)66992-9.
3
Undue inducement in clinical research.
Lancet. 2005;366(9482):275-6. doi: 10.1016/S0140-6736(05)66964-4.
4
Undue fear of inducements in research in developing countries.
Camb Q Healthc Ethics. 2009 Apr;18(2):122-9. doi: 10.1017/S0963180109090215.
5
Universal and uniform protection of human subjects in research: also a fallacy in some developing countries.
Am J Bioeth. 2008 Nov;8(11):19-20. doi: 10.1080/15265160802478479.
6
Protecting the vulnerable: testing times for clinical research ethics.
Soc Sci Med. 2000 Sep;51(6):969-77. doi: 10.1016/s0277-9536(00)00075-7.
7
Translational research beyond approval: a two-stage ethics review.
Am J Bioeth. 2010 Aug;10(8):W1-3. doi: 10.1080/15265161.2010.500199.
8
Benefits to research subjects in international trials: do they reduce exploitation or increase undue inducement?
Dev World Bioeth. 2008 Dec;8(3):178-91. doi: 10.1111/j.1471-8847.2006.00175.x.
9
[Clinical trials in developing countries: who should define ethics?].
Bull Soc Pathol Exot. 2008 Apr;101(2):102-5.
10
Clinical trials for children: some concerns.
Indian J Pharmacol. 2014 Mar-Apr;46(2):145-6. doi: 10.4103/0253-7613.129300.
引用本文的文献
1
Analysis of control arms in oncology randomised trials in Brazil: a cross-sectional study.
BMJ Oncol. 2025 Aug 4;4(1):e000808. doi: 10.1136/bmjonc-2025-000808. eCollection 2025.
2
Efficacy of Extended Antibiotic Prophylaxis with Azithromycin in Cesarean Sections.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 4):S3370-S3373. doi: 10.4103/jpbs.jpbs_783_24. Epub 2024 Oct 28.
3
Perceptions, experiences, and motivation of COVID-19 vaccine trial participants in South Africa: a qualitative study.
Res Integr Peer Rev. 2024 Jul 29;9(1):8. doi: 10.1186/s41073-024-00148-6.
4
Incorporating Anti-racist Principles Throughout the Research Lifecycle: A Position Statement from the Society of General Internal Medicine (SGIM).
J Gen Intern Med. 2024 Aug;39(10):1922-1931. doi: 10.1007/s11606-024-08770-2. Epub 2024 May 14.
5
Global Disparities in Access to Vaccine Clinical Trials: A Review of the Literature.
Vaccines (Basel). 2024 Mar 23;12(4):348. doi: 10.3390/vaccines12040348.
6
Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions.
BMJ Open. 2024 Apr 15;14(4):e077132. doi: 10.1136/bmjopen-2023-077132.
7
Representation from India in multinational, interventional, phase 2 or 3 trials registered in Clinical Trials Registry-India: A cross-sectional study.
PLoS One. 2023 Sep 20;18(9):e0284434. doi: 10.1371/journal.pone.0284434. eCollection 2023.
8
GO-Tibia: a masked, randomized control trial evaluating gentamicin versus saline in open tibia fractures.
Trials. 2023 Jun 15;24(1):406. doi: 10.1186/s13063-023-07410-0.
9
Viral etiology of lower respiratory tract infections in adults in the pre-COVID-19 pandemic era: A cross-sectional study in a single center experience from Cameroon.
Health Sci Rep. 2023 Apr 26;6(5):e1234. doi: 10.1002/hsr2.1234. eCollection 2023 May.
10
Current Clinical Landscape and Global Potential of Bacteriophage Therapy.
Viruses. 2023 Apr 21;15(4):1020. doi: 10.3390/v15041020.
本文引用的文献
1
Ethical and scientific implications of the globalization of clinical research.
N Engl J Med. 2009 Feb 19;360(8):816-23. doi: 10.1056/NEJMsb0803929.
2
Sharing benefits in international health research. Research-capacity building as an example of an indirect collective benefit.
EMBO Rep. 2007 Jan;8(1):8-13. doi: 10.1038/sj.embor.7400886.
3
The battle of Helsinki: two troublesome paragraphs in the Declaration of Helsinki are causing a furore over medical research ethics.
EMBO Rep. 2006 Jul;7(7):670-2. doi: 10.1038/sj.embor.7400743.
Zotero 插件