Byard R W
Department of Paediatrics, University of Adelaide, Adelaide, Australia; Department of Histopathology, Women's and Children's Hospital, Adelaide, Australia.
Cardiovasc Pathol. 1996 Sep-Oct;5(5):243-57. doi: 10.1016/1054-8807(96)00042-7.
Vascular causes of sudden death in infancy, childhood, and adolescence range from primary disorders of the vasculature involving structural compromise, as in anomalous coronary arteries, to vascular problems that may arise as secondary phenomena, such as the infectious arteritides. The etiology of the underlying condition may be understood, as in fatal pulmonary thromboembolism, or it may be shrouded in mystery, as in idiopathic arterial calcinosis. The absence of a clinical history indicating an underlying vascular problem in a number of disorders that may cause sudden childhood death underlines the importance of a meticulous autopsy examination in such cases.
婴儿期、儿童期及青少年期猝死的血管病因范围广泛,从涉及结构受损的原发性血管疾病(如冠状动脉异常)到可能作为继发现象出现的血管问题(如感染性动脉炎)。潜在病症的病因可能是已知的,如致命性肺血栓栓塞;也可能是不明的,如特发性动脉钙化。在许多可能导致儿童期猝死的病症中,缺乏提示潜在血管问题的临床病史凸显了在此类病例中进行细致尸检的重要性。