Isoyama-Shirakawa Yuko, Nakamura Katsumasa, Abe Madoka, Kunitake Naonobu, Matsumoto Keiji, Ohga Saiji, Sasaki Tomonari, Uehara Satoru, Okushima Kazuhiro, Shioyama Yoshiyuki, Honda Hiroshi
Department of Radiation Oncology, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
J Radiat Res. 2015 May;56(3):583-7. doi: 10.1093/jrr/rrv011. Epub 2015 Apr 6.
It has been suggested that pain control during intracavitary brachytherapy for cervical cancer is insufficient in most hospitals in Japan. Our hospital began using caudal epidural anesthesia during high-dose-rate (HDR) intracavitary brachytherapy in 2011. The purpose of the present study was to retrospectively investigate the effects of caudal epidural anesthesia during HDR intracavitary brachytherapy for cervical cancer patients. Caudal epidural anesthesia for 34 cervical cancer patients was performed during HDR intracavitary brachytherapy between October 2011 and August 2013. We used the patients' self-reported Numeric Rating Scale (NRS) score at the first session of HDR intracavitary brachytherapy as a subjective evaluation of pain. We compared NRS scores of the patients with anesthesia with those of 30 patients who underwent HDR intracavitary brachytherapy without sacral epidural anesthesia at our hospital between May 2010 and August 2011. Caudal epidural anesthesia succeeded in 33 patients (97%), and the NRS score was recorded in 30 patients. The mean NRS score of the anesthesia group was 5.17 ± 2.97, significantly lower than that of the control group's 6.80 ± 2.59 (P = 0.035). The caudal epidural block resulted in no side-effects. Caudal epidural anesthesia is an effective and safe anesthesia option during HDR intracavitary brachytherapy for cervical cancer.
有人认为,在日本大多数医院,宫颈癌腔内近距离放射治疗期间的疼痛控制不足。我院于2011年开始在高剂量率(HDR)腔内近距离放射治疗期间使用骶管硬膜外麻醉。本研究的目的是回顾性调查骶管硬膜外麻醉在宫颈癌患者HDR腔内近距离放射治疗期间的效果。2011年10月至2013年8月期间,对34例宫颈癌患者在HDR腔内近距离放射治疗期间实施了骶管硬膜外麻醉。我们将患者在HDR腔内近距离放射治疗第一疗程时自我报告的数字评分量表(NRS)评分作为疼痛的主观评估。我们将接受麻醉的患者的NRS评分与2010年5月至2011年8月期间在我院接受HDR腔内近距离放射治疗但未进行骶管硬膜外麻醉的30例患者的评分进行了比较。骶管硬膜外麻醉在33例患者(97%)中成功实施,30例患者记录了NRS评分。麻醉组的平均NRS评分为5.17±2.97,显著低于对照组的6.80±2.59(P=0.035)。骶管硬膜外阻滞未产生副作用。骶管硬膜外麻醉是宫颈癌HDR腔内近距离放射治疗期间一种有效且安全的麻醉选择。